Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.1K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.1K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

492
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
492
Spontaneity02:21

Spontaneity

30.1K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
30.1K
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

283
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
283
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

391
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
391
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

703
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
703

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RETRACTED: Russo et al. Chamazulene-Rich <i>Artemisia arborescens</i> Essential Oils Affect the Cell Growth of Human Melanoma Cells. <i>Plants</i> 2020, <i>9</i>, 1000.

Plants (Basel, Switzerland)·2026
Same author

Echocardiographic Parameters and Athlete Performance: Associations and Training Profile Comparisons.

Echocardiography (Mount Kisco, N.Y.)·2026
Same author

Evaluation Profile of Sicilian <i>Oenanthe aquatica</i> (L.) Poir., <i>O. fistulosa</i> L. and <i>O. pimpinelloides</i> L. Essential Oils Under LPS-Induced Cellular Stress.

Plants (Basel, Switzerland)·2026
Same author

Does the Fissure Last Technique Really Reduce Postoperative Airleak After Lung Resection? Results From a Prospective Randomized Controlled Trial.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Is Ventilatory Equivalent for Carbon Dioxide (VE/VCO2) Slope the Key to Reduce Mortality in Patients Undergoing Pneumonectomy?

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same author

Inflammatory bowel disease (IBD) is associated with increased intestinal extrachromosomal circular DNA: an emerging biomarker for IBD type and activity.

Journal of Crohn's & colitis·2025
Same journal

Giornale italiano di cardiologia (2006)·2026
Same journal

[Green paper ANMCO: Environmental sustainability in cardiology: a shared commitment of healthcare professionals].

Giornale italiano di cardiologia (2006)·2026
Same journal

[Bempedoic acid in real-world clinical practice: baseline and 8-week data from the Italian prospective, non-interventional MILOS study].

Giornale italiano di cardiologia (2006)·2026
Same journal

[Ranolazine: established indications and emerging therapeutic potential].

Giornale italiano di cardiologia (2006)·2026
Same journal

[Kawasaki disease: the update of American Heart Association guidelines. What adult cardiologists need to know].

Giornale italiano di cardiologia (2006)·2026
Same journal

[The application of artificial intelligence in arrhythmology].

Giornale italiano di cardiologia (2006)·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.2K

[Spontaneous coronary artery dissections].

Alessandra Russo1, Corrado Lettieri2, Salvatore Ivan Caico3

  • 1Cardiologia Interventistica, ASST Valle Olona, Presidio di Gallarate (VA).

Giornale Italiano Di Cardiologia (2006)
|August 9, 2018
PubMed
Summary
This summary is machine-generated.

Spontaneous coronary artery dissection (SCAD) is a key cause of heart disease in young women. While often treated conservatively with good outcomes, SCAD requires careful monitoring due to recurrence risks and potential for other arterial issues.

More Related Videos

Modified Technique for Coronary Artery Ligation in Mice
05:47

Modified Technique for Coronary Artery Ligation in Mice

Published on: March 29, 2013

26.6K
Use of a Hanging Weight System for Coronary Artery Occlusion in Mice
08:30

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

22.1K

Related Experiment Videos

Last Updated: Feb 6, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.2K
Modified Technique for Coronary Artery Ligation in Mice
05:47

Modified Technique for Coronary Artery Ligation in Mice

Published on: March 29, 2013

26.6K
Use of a Hanging Weight System for Coronary Artery Occlusion in Mice
08:30

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

22.1K

Area of Science:

  • Cardiology
  • Vascular Biology
  • Medical Imaging

Background:

  • Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic condition affecting coronary arteries, predominantly in women aged 40-50.
  • It is a significant cause of myocardial ischemia and heart disease, often occurring in individuals with minimal cardiovascular risk factors.
  • Increased diagnosis rates are linked to advancements in coronary angiography and intracoronary imaging techniques.

Purpose of the Study:

  • To review the pathology, diagnosis, and management of SCAD.
  • To highlight the role of advanced imaging in SCAD detection.
  • To discuss therapeutic strategies and long-term prognosis for SCAD patients.

Main Methods:

  • Review of current literature on SCAD.
  • Analysis of diagnostic modalities including coronary angiography, intravascular ultrasound (IVUS), and optical coherence tomography (OCT).
  • Discussion of conservative management approaches and follow-up protocols.

Main Results:

  • SCAD involves separation of coronary artery wall layers, leading to intramural hematoma and lumen compromise.
  • Coronary angiography is the primary diagnostic tool, complemented by IVUS and OCT for detailed imaging.
  • Conservative therapy is favored due to high rates of spontaneous vascular healing, with good prognosis but a notable risk of recurrence.

Conclusions:

  • SCAD is a distinct cause of acute coronary syndrome, particularly in younger women.
  • Effective management relies on accurate diagnosis and conservative treatment, emphasizing long-term surveillance.
  • Screening for associated arterial dissections and aneurysms is recommended due to potential systemic implications.