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Updated: Feb 6, 2026

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Uveal effusion syndrome – a case study.

Iwona Grabska-Liberek, Katarzyna Zagajewska, Jacek Kosmala

    Klinika Oczna
    |August 9, 2018
    PubMed
    Summary

    A 63-year-old female with uveal effusion syndrome and nanophthalmos experienced vision loss. Treatment with NSAIDs, sclerectomy, and mitomycin C successfully resolved retinal detachment, with no recurrence during follow-up.

    Area of Science:

    • Ophthalmology
    • Retinal Diseases

    Background:

    • Uveal effusion syndrome (UES) is a rare condition characterized by the accumulation of fluid in the suprachoroidal space.
    • Nanophthalmos is a developmental disorder associated with a small, hyperopic eye.

    Observation:

    • A 63-year-old female presented with decreased vision in her right eye.
    • Bilateral uveal effusion syndrome concomitant with nanophthalmos was diagnosed.

    Findings:

    • The patient received systemic non-steroidal anti-inflammatory drugs (NSAIDs) and underwent sclerectomy with topical mitomycin C.
    • Gradual resolution of retinal detachment was observed over 2 months, with complete reattachment.
    • No recurrence of retinal detachment was noted during long-term follow-up.

    Implications:

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    • This case highlights a successful multimodal treatment approach for retinal detachment secondary to uveal effusion syndrome and nanophthalmos.
    • Sclerectomy combined with mitomycin C may be an effective option for managing complex retinal detachments in these patients.
    • Further research is warranted to elucidate the pathophysiology and optimize treatment strategies for uveal effusion syndrome and nanophthalmos.