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Updated: Feb 6, 2026

Deep Learning-Based Segmentation of Cryo-Electron Tomograms
Published on: November 11, 2022
Low-rank and sparse decomposition with spatially adaptive filtering for sequential segmentation of 2D+t vessels
Mingxin Jin1, Dongdong Hao1, Song Ding2
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.
Abstract:
This letter proposes to extract contrast-filled vessels from overlapped noisy complex backgrounds in an x-ray coronary angiogram image sequence using low-rank and sparse decomposition. A refined vessel segmentation is finally achieved by implementing a radon-like feature filtering plus local-to-global adaptive thresholding to tackle the spatially varying noisy residuals in the extracted vessels. Based on real and synthetic XCA data, the experiment results demonstrate the superiority of the proposed method over the state-of-the-art methods.
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