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Related Concept Videos

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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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A household microwave and lasers are examples of standing electromagnetic waves in a cavity. When two conducting metal plates are placed parallel at the nodal planes, it creates a cavity where standing waves are formed. The cavity between the two planes is analogous to a stretched string held at the points x = 0 and x = L. Here, the distance 'L' between the two planes must be an integer multiple of half of the wavelength. The wavelengths that satisfy this condition are given by:
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Cavity walls feature a hollow space between the outer and inner wythes, connected only by corrosion-resistant metal ties. When water seeps through the outer wythe, it descends within this cavity, intercepted by flashing and eventually exiting through weep holes. To enhance moisture resistance, the inner wythe's cavity side often receives damp-proofing, doubling as an air barrier. The cavity can also house insulation to mitigate heat transfer.
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Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
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Related Experiment Video

Updated: Feb 6, 2026

The Slice Culture Method for Following Development of Tooth Germs In Explant Culture
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Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers.

Jan Schlueter1, Takashi Mikawa1

  • 1University of California San Francisco, School of Medicine, Cardiovascular Research Institute, 555 Mission Bay Blvd South, San Francisco, CA 94158, USA.

Cell Reports
|August 9, 2018
PubMed
Summary
This summary is machine-generated.

Mesodermal cells form projections to receive BMP7 from the ectoderm, a crucial step for body cavity development. This signaling pathway is essential for organogenesis and understanding developmental biology.

Keywords:
BMP7body cavityectodermfilopodiamesoderm

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Area of Science:

  • Developmental Biology
  • Cell Biology
  • Molecular Biology

Background:

  • The body cavity is vital for internal organ development and placement.
  • Mechanisms of body cavity formation within the mesoderm are not well understood.

Purpose of the Study:

  • To investigate the process of body cavity formation in the mesoderm.
  • To identify signaling pathways involved in dorsal mesoderm development.

Main Methods:

  • Observation of dorsal mesodermal cell polarization and lumen formation.
  • Analysis of cell projections directed towards the ectoderm.
  • Investigating the role of ectodermal BMP7 signaling.

Main Results:

  • Mesodermal cells form filamentous projections towards the ectoderm upon polarization.
  • These projections facilitate the reception of BMP7 from the ectoderm.
  • Suppression of BMP7 disrupts cell projections and body cavity formation.

Conclusions:

  • Body cavity induction relies on signaling factor transfer from ectoderm to mesoderm.
  • Ectodermal BMP7 is essential for mesodermal cell projection and body cavity development.
  • This study elucidates a key mechanism in embryonic development.