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Effect of gastrocystoplasty on height and bone density in children

Amit Singh1, G Moorthy1, Minu Bajpai1

  • 1Department of Pediatric Surgery, All India Institute of Medical Sciences (AIIMS), New Delhi, India.

Urology Annals
|August 10, 2018
PubMed

Insights

Augmentation gastrocystoplasty is a safe procedure for bladder exstrophy patients, showing no adverse effects on height or bone mineral density. This surgical option maintains metabolic and acid-base balance, supporting long-term patient health.

Area of Science:

  • Pediatric Urology
  • Surgical Innovation
  • Metabolic Health

Background:

  • Urinary tract augmentation with gastrointestinal tissue can cause metabolic alterations.
  • Bladder exstrophy necessitates reconstructive surgery, often involving augmentation cystoplasty.

Purpose of the Study:

  • To evaluate the long-term effects of augmentation gastrocystoplasty on growth and bone health in bladder exstrophy patients.
  • To assess metabolic and acid-base homeostasis following the procedure.

Main Methods:

  • A cross-sectional study combining retrospective and prospective analyses of patients who underwent gastrocystoplasty.
  • Bone mineral density was assessed using dual-energy X-ray absorptiometry (DXA).
  • Growth parameters were compared against Indian standard growth charts.

Main Results:

  • Twenty-three patients (16 male, 7 female) with a mean follow-up of 60 months were analyzed.
  • Patients showed no significant adverse effects on height or bone mineral density post-augmentation.
  • Metabolic and acid-base parameters remained within normal limits.

Conclusions:

  • Augmentation gastrocystoplasty is a safe and effective surgical option for bladder exstrophy.
  • The procedure does not negatively impact patient height or bone mineral density.
  • Long-term metabolic and acid-base homeostasis is preserved.
Abstract

Keywords:
Bone mineral densityexstrophy bladderphysical growth

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