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Paget's Disease of Bone: An Entity Still Exists in India
Kripa Elizabeth Cherian1, Nitin Kapoor1, Sahana Shetty1
1Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India.
Background:
Paget's disease of bone (PDB) is uncommonly reported from India. We attempted to study the clinical and imaging features and management of participants who presented with PDB.
Materials And Methods:
In this retrospective study, clinical and imaging profile, biochemistry, and treatment outcomes of participants with PDB (n = 48) were obtained.
Results:
The mean age was 60 ± 11.3 years and 35% were women. Twenty percent were asymptomatic. Many (87%) had polyostotic involvement. Sixty percent (n = 29) underwent treatment with zoledronic acid and rest with oral bisphosphonates, and all achieved remission.
Conclusion:
Most of the pagetic participants had polyostotic disease and one-fifth were asymptomatic. All participants had disease remission following treatment.