Related Experiment Video
Updated: Feb 6, 2026

Utilizing 3D Printing Technology to Merge MRI with Histology: A Protocol for Brain Sectioning
Published on: December 6, 2016
Air bubble artifact reduction in post-mortem whole-brain MRI: the influence of receiver bandwidth
Max Scheffler1, Enrique Maturana2, Rares Salomir3,4
1Department of Radiology, Geneva University Hospitals, Ch. du Pont-Bochet 3, 1226, Thonex, Switzerland. max.scheffler@hcuge.ch.
Abstract:
Air bubble artifacts on SWI post-mortem MRI studies may interfere with the detection of cerebral microbleeds. We investigated whether the utilization of a higher receiver bandwidth of 500 Hz/pixel could reduce cortical air bubble artifacts without compromising the detection of cerebral microbleeds in high-field MRI. All microbleeds remained clearly visible whereas a reduction of 17% of the long axis of the "halo" magnitude artifacts was achieved. On corresponding phase images, air bubble artifacts appeared identical.
Insights
Higher receiver bandwidth in post-mortem MRI reduces air bubble artifacts on susceptibility-weighted imaging (SWI). This technique maintained clear visualization of cerebral microbleeds, improving image quality for post-mortem brain analysis.
Area of Science:
- Neuroimaging
- Radiology
- Post-mortem studies
Background:
- Air bubble artifacts in susceptibility-weighted imaging (SWI) can hinder cerebral microbleed detection in post-mortem MRI.
- Accurate identification of microbleeds is crucial for neuropathological research.
Purpose of the Study:
- To evaluate if a higher receiver bandwidth (500 Hz/pixel) can minimize cortical air bubble artifacts.
- To determine if this modification compromises the detection of cerebral microbleeds in high-field MRI.
Main Methods:
- Utilized a higher receiver bandwidth (500 Hz/pixel) during SWI acquisition in post-mortem MRI.
- Compared artifact reduction and microbleed visibility with standard bandwidth settings.
Main Results:
- A 17% reduction in the long axis of "halo" magnitude artifacts was observed.
- All cerebral microbleeds remained clearly visible on images acquired with the higher bandwidth.
- Air bubble artifacts appeared identical on corresponding phase images.
Conclusions:
- Increasing receiver bandwidth is an effective method to reduce air bubble artifacts in post-mortem SWI.
- This technique preserves the sensitivity for detecting cerebral microbleeds, enhancing diagnostic accuracy.
More Related Videos
08:19Protocol for the Evaluation of MRI Artifacts Caused by Metal Implants to Assess the Suitability of Implants and the Vulnerability of Pulse Sequences
Published on: May 17, 2018
08:46A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
Published on: March 7, 2017
Related Concept Videos
Excess Pressure Inside a Drop and a Bubble
Oxidation-Reduction Reactions
Receiver Operating Characteristic Plot
Air-entraining Agents
Effects of Air-entrainment in Concrete
The Influence of Affect on Cognition