Air bubble artifact reduction in post-mortem whole-brain MRI: the influence of receiver bandwidth

Max Scheffler1, Enrique Maturana2, Rares Salomir3,4

  • 1Department of Radiology, Geneva University Hospitals, Ch. du Pont-Bochet 3, 1226, Thonex, Switzerland. max.scheffler@hcuge.ch.

Neuroradiology
|August 10, 2018
PubMed

Insights

Higher receiver bandwidth in post-mortem MRI reduces air bubble artifacts on susceptibility-weighted imaging (SWI). This technique maintained clear visualization of cerebral microbleeds, improving image quality for post-mortem brain analysis.

Area of Science:

  • Neuroimaging
  • Radiology
  • Post-mortem studies

Background:

  • Air bubble artifacts in susceptibility-weighted imaging (SWI) can hinder cerebral microbleed detection in post-mortem MRI.
  • Accurate identification of microbleeds is crucial for neuropathological research.

Purpose of the Study:

  • To evaluate if a higher receiver bandwidth (500 Hz/pixel) can minimize cortical air bubble artifacts.
  • To determine if this modification compromises the detection of cerebral microbleeds in high-field MRI.

Main Methods:

  • Utilized a higher receiver bandwidth (500 Hz/pixel) during SWI acquisition in post-mortem MRI.
  • Compared artifact reduction and microbleed visibility with standard bandwidth settings.

Main Results:

  • A 17% reduction in the long axis of "halo" magnitude artifacts was observed.
  • All cerebral microbleeds remained clearly visible on images acquired with the higher bandwidth.
  • Air bubble artifacts appeared identical on corresponding phase images.

Conclusions:

  • Increasing receiver bandwidth is an effective method to reduce air bubble artifacts in post-mortem SWI.
  • This technique preserves the sensitivity for detecting cerebral microbleeds, enhancing diagnostic accuracy.

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