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Research Progress of Raman Spectroscopy in Drug Analysis
Wen-Ting Wang1, Hua Zhang2, Yuan Yuan3
1Wanzhou Institute for Food and Drug Control, Chongqing, 404000, China. wenting92w@163.com.
Abstract:
Raman spectroscopy is a spectroscopic analysis technique that enables rapid qualitative and quantitative detection based on inelastic collision and Raman scattering intensity. This review detailed the generation principle, instrument composition, influencing factors, and common classifications of Raman spectrum. Furthermore, it summarized and forecast the research progress of Raman spectroscopy in the field of drug analysis simultaneously over the past decade, including the identification of active pharmaceutical ingredients (APIs), qualitative and quantitative studies of pharmaceutical preparations, detection of illicit drugs, the identification of Chinese herbal medicines, and the combination with other technologies. The development of Raman spectroscopy in other fields is additionally summarized.
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