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Related Experiment Videos

Studies on prolactin in human milk.

Y Taketani, M Mizuno

    Endocrinologia Japonica
    |December 1, 1985
    PubMed
    Summary

    Human milk contains significant amounts of biologically active prolactin (PRL). This suggests that milk prolactin may play an important physiological role for newborns, despite no correlation with milk yield.

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    Area of Science:

    • Endocrinology
    • Human Lactation
    • Neonatal Physiology

    Background:

    • Prolactin (PRL) is a key hormone in lactation.
    • Its presence and role in human milk are not fully understood.
    • Investigating PRL's physiological significance for newborns is crucial.

    Purpose of the Study:

    • To investigate the potential physiological role of prolactin (PRL) in human milk.
    • To quantify milk PRL concentrations and assess their biological activity.

    Main Methods:

    • Quantification of immunoreactive prolactin (PRL) in human milk samples.
    • Assessment of milk PRL's ability to bind to its receptors.

    Main Results:

    • Milk PRL concentrations were high, peaking on the second day postpartum.
    • Milk PRL demonstrated receptor-binding capacity, indicating biological potency.
    • No significant correlation was found between milk PRL levels and milk yield.

    Conclusions:

    • Human milk contains substantial amounts of immunoreactive prolactin.
    • Milk PRL is biologically potent and may have physiological significance for newborns.
    • Further research is warranted to elucidate the specific roles of milk PRL in neonatal development.

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