Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Global Climate Change01:50

Global Climate Change

29.0K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
29.0K
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

1.8K
Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
1.8K
Noncompartmental Analysis: Mean Residence Time01:05

Noncompartmental Analysis: Mean Residence Time

611
According to statistical moment theory, mean residence time (MRT) is an important measure in pharmacokinetics. MRT can be defined as the expected mean of a probability density function distribution. It provides valuable insights into drug disposition in the body.
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
611
Introduction to Global Positioning System01:30

Introduction to Global Positioning System

541
The Global Positioning System (GPS) revolutionized positioning on Earth, providing precise location data through satellite ranging. The GPS system was developed in 1978 by the U.S. Department of Defense  for military use, and it became available for civilian applications in 1983, transforming fields including navigation, fleet management, and time synchronization for telecommunications systems.GPS consists of satellites in medium Earth orbit, about 20,200 kilometers above the surface,...
541
Errors in Global Positioning System01:26

Errors in Global Positioning System

356
Global Positioning System (GPS) technology has revolutionized navigation and positioning, but its accuracy is often compromised by various errors. These errors, stemming from environmental, satellite, and receiver-related factors, require careful mitigation to ensure reliable performance across applications.Atmospheric ErrorsGPS signals travel through the Earth’s ionosphere and troposphere, introducing delays which affect accuracy. The ionosphere is strongly influenced by charged particles,...
356
Global Regulatory Systems01:28

Global Regulatory Systems

692
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
692

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photochemistry of CryB from Rhodobacter sphaeroides.

Photochemistry and photobiology·2026
Same author

Insights into epidemiological and clinical burden of bronchiolitis among hospitalized children: a call for preventive interventions.

Frontiers in pediatrics·2026
Same author

Fluorinated Tryptophan Derivatives for Photo-CIDNP NMR.

The journal of physical chemistry. B·2026
Same author

Optically detected and radio wave-controlled spin chemistry in flavoproteins.

Nature biotechnology·2026
Same author

Nanosecond Structure of Radical Pair Intermediates from High-Frequency Quantum Oscillations: Insight into the Q<sub>A</sub><sup>•-</sup> to Q<sub>B</sub> Electron Transfer Step in Purple Bacterial Photosynthesis.

The journal of physical chemistry. B·2026
Same author

Trends in antimicrobial resistance associated with gastrointestinal tract infections in the UAE: A comprehensive retrospective surveillance 13-year (2010-2022) study.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Related Experiment Video

Updated: Feb 6, 2026

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing
07:41

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing

Published on: February 4, 2017

8.9K

Global analysis of complex PELDOR time traces.

Stephan Rein1, Philipp Lewe2, Susana L Andrade3

  • 1Institut für Physikalische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, 79104 Freiburg, Germany.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|August 10, 2018
PubMed
Summary
This summary is machine-generated.

A new Python tool, GloPel, enhances analysis of Pulsed Electron-Electron Double Resonance (PELDOR) data. It improves distance distribution accuracy, especially with noisy, long-time echo decay measurements.

Keywords:
Ammonium transporterAmt1DEERGlobal analysisGlobal fittingPELDORTikhonov regularization

More Related Videos

Global Gene Expression Analysis Using a Zebrafish Oligonucleotide Microarray Platform
13:14

Global Gene Expression Analysis Using a Zebrafish Oligonucleotide Microarray Platform

Published on: August 10, 2009

12.2K
Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers MADM
09:25

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers MADM

Published on: May 8, 2020

11.3K

Related Experiment Videos

Last Updated: Feb 6, 2026

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing
07:41

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing

Published on: February 4, 2017

8.9K
Global Gene Expression Analysis Using a Zebrafish Oligonucleotide Microarray Platform
13:14

Global Gene Expression Analysis Using a Zebrafish Oligonucleotide Microarray Platform

Published on: August 10, 2009

12.2K
Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers MADM
09:25

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers MADM

Published on: May 8, 2020

11.3K

Area of Science:

  • Electron Paramagnetic Resonance (EPR) Spectroscopy
  • Biophysics
  • Materials Science

Background:

  • Pulsed electron-electron double resonance (PELDOR) detects electron spin interactions.
  • Longer observation times are needed for distant spins, but signal-to-noise ratio decreases.
  • This limits accurate distance distribution analysis in PELDOR.

Purpose of the Study:

  • To introduce GloPel, an open-source Python application for PELDOR data analysis.
  • To enable extraction of high-quality distance distributions from noisy or incomplete PELDOR data.
  • To improve accuracy and reduce measurement time for PELDOR experiments.

Main Methods:

  • Development of GloPel, a Python-based PELDOR analysis tool.
  • Implementation of Tikhonov regularization for simultaneous analysis of multiple time traces.
  • Utilizing two different observation time windows for data acquisition.

Main Results:

  • GloPel allows accurate distance distribution analysis even with low signal-to-noise ratios.
  • Simultaneous analysis of short and long time traces overcomes limitations of individual windows.
  • The method prevents overlooking short distances and artificially shortening long distances.

Conclusions:

  • GloPel provides improved distance measurements from PELDOR data.
  • The tool enhances data quality and can reduce experimental time.
  • GloPel is a valuable open-source resource for PELDOR researchers.