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Updated: Feb 6, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Perceived Synergistic Risk for Lung Cancer After Environmental Report-Back Study on Home Exposure to Tobacco Smoke
Karen M Butler1, Luz Huntington-Moskos2, Mary Kay Rayens3
11 Radon Policy Division, BREATHE, College of Nursing, University of Kentucky, Lexington, KY, USA.
Purpose:
To examine the short-term impact of a personalized environmental report-back intervention to reduce home exposure to tobacco smoke and radon on perception of synergistic risk for lung cancer. Radon-induced lung cancer is more common among those exposed to tobacco smoke.
Design:
Randomized controlled trial.
Setting:
Primary care clinics and a pharmacy waiting area at a University Medical Center in the Southeastern United States and community events.
Participants:
Five hundred sixty adult homeowners and renters (3-month follow-up, n = 334).
Intervention:
Personalized environmental report back.
Measures:
Single-item synergistic risk perception measure using 5-point Likert-type scale.
Analysis:
Change in synergistic risk from baseline to 3 months was evaluated using a generalized estimating equation model containing main effects of treatment group and time. Covariates in the model included age, gender, education, and home smoking status.
Results:
For treatment and control groups combined, there was a significant increase in perception of synergistic risk from baseline to 3 months, but the study groups did not differ. There was no association between perceived synergistic risk and whether or not there were smokers at home.
Conclusion:
Learning about combined risks for lung cancer, with or without dual home screening for secondhand smoke and radon and environmental report-back, may enhance perceived risk for combined environmental exposures. Evaluation of perceived synergistic risk with a single item is a study limitation.
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