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Published on: December 8, 2010
[Contiguous cutaneous inflammation secondary to an aspergillus sinusitis]
H Lefranc1, C Brugière1, L Plisson2
1Service de dermatologie, CHU de Caen, avenue de la Côte-de-Nacre, 14033 Caen, France; Faculté de médecine, université de Caen Normandie, avenue de la Côte-de-Nacre, 14000 Caen, France.
Contiguous skin inflammation, a rare condition, can stem from sinusitis. This case highlights the first instance of Aspergillus sinusitis causing facial inflammation, successfully treated with antifungal medication and surgery.
Area of Science:
- Dermatology
- Otolaryngology
- Infectious Diseases
Background:
- Contiguous skin inflammation is an uncommon manifestation of underlying infectious, inflammatory, or neoplastic processes.
- Sinusitis is a recognized cause of contiguous skin inflammation.
Purpose of the Study:
- To report a novel case of contiguous skin inflammation linked to Aspergillus sinusitis.
- To describe the successful treatment of this rare condition.
Main Methods:
- A case study of a 70-year-old patient with a centrofacial inflammatory plaque.
- Diagnostic procedures included skin biopsy, CT scan, and intra-sinus sampling.
- Treatment involved voriconazole and maxillary sinus surgery.
Main Results:
- Skin biopsy showed polymorphic inflammatory infiltrate; cultures were negative.
- CT scan revealed left maxillary sinusitis.
- Intra-sinus samples identified Aspergillus; treatment led to plaque resolution.
Conclusions:
- This is the third reported case of contiguous skin inflammation associated with sinusitis.
- This case represents the first documented instance of contiguous skin inflammation caused by Aspergillus sinusitis.
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