Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Barriers and enablers to medical students' engagement in research and clinical academic careers: a mixed-methods study.

BMJ open·2025

Same author

The Regulation of Catecholamine Biosynthesis by the Gas Transmitters Carbon Monoxide and Hydrogen Sulfide.

Current issues in molecular biology·2025

Same author

Parents' Industrial Sectors and Fields of Study: Five Decades of Evidence from an Elite Regional University in China.

Sociology·2025

Same author

Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP.

Proceedings of the National Academy of Sciences of the United States of America·2025

Same author

Preterm Birth and Risk of Health Service Use, Morbidity, and Medication Needs at 5 Years.

JAMA pediatrics·2025

Same author

Nucleotide-dependent conformational changes direct peptide export by the transporter associated with antigen processing.

Immunity·2025

Search research articles

Related Experiment Video

Updated: Feb 6, 2026

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

Published on: April 30, 2020

Eighty-two-year-old man with a systolic murmur.

Daniel F Kupsky¹, Karthikeyan Ananthasubramaniam¹, James Lee¹

¹Department of Medicine Division of Cardiology, Henry Ford Hospital Heart and Vascular Institute, Detroit, Michigan, USA.

Heart (British Cardiac Society)

|August 11, 2018

Summary

This clinical case study highlights severe mitral stenosis in an elderly male patient undergoing cardiac risk evaluation. Echocardiography revealed characteristic Doppler findings indicative of this significant valvular heart disease.

Keywords:

echocardiography valvular heart diseas

More Related Videos

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Published on: January 16, 2013

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling

Published on: November 17, 2019

Related Experiment Videos

Last Updated: Feb 6, 2026

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

Published on: April 30, 2020

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Published on: January 16, 2013

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling

Published on: November 17, 2019

Area of Science:

Cardiology
Cardiac Imaging
Valvular Heart Disease

Background:

Pre-operative cardiac risk assessment is crucial for elderly patients with comorbidities undergoing non-cardiac surgery.
The patient presented for evaluation prior to resection of a small bowel gastrointestinal stromal tumour.
He had a history of coronary artery bypass surgery, hypertension, and a low activity level.

Observation:

Physical examination revealed a 2/6 systolic murmur at the apex.
Electrocardiogram (ECG) showed normal sinus rhythm.
Transthoracic echocardiography was performed for further cardiac evaluation.

Findings:

Echocardiographic Doppler tracings of the mitral valve (Figure 1A) demonstrated findings consistent with severe mitral stenosis.
Tricuspid valve Doppler (Figure 1B) was also analyzed.

Implications:

Accurate diagnosis of severe mitral stenosis is critical for surgical planning and patient management.
This case underscores the importance of echocardiography in identifying significant valvular heart disease in asymptomatic patients.
Management strategies must address both the oncological and cardiovascular conditions.