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Assessment of physical function in children with cancer: A systematic review
Sarah L Grimshaw1,2, Nicholas F Taylor1, Francoise Mechinaud2
1School of Allied Health, La Trobe University, Melbourne, Victoria, Australia.
Insights
Selecting the right physical function assessment tools for children with cancer is crucial. Current evidence is limited, with no single tool consistently recommended due to poor study quality.
Area of Science:
- Pediatric Oncology
- Rehabilitation Medicine
- Clinical Measurement
Background:
- Monitoring physical function in pediatric cancer patients during and after treatment is vital.
- Robust assessment tools are necessary for accurate evaluation.
- This review focuses on physical function measures for children with cancer.
Purpose of the Study:
- To systematically identify and critically appraise measurement properties of physical function measures used in children with cancer.
- To evaluate the evidence supporting the use of these measures in this specific population.
- To guide the selection of appropriate assessment tools.
Main Methods:
- Conducted systematic searches across seven electronic databases.
- Identified 101 physical function measures from 154 studies.
- Critically appraised methodological quality and measurement properties using the COSMIN framework.
Main Results:
- Data on measurement properties were available for only 12 measures.
- Only two measures were assessed in more than one study.
- No assessment tool demonstrated consistent, adequate evidence for use in childhood cancer populations, often due to poor study quality.
Conclusions:
- Limited population-specific evidence exists to guide the selection of physical function measures for children with cancer.
- Further research is needed to establish the reliability, validity, and responsiveness of these measures.
- Improved assessment tools are essential for effective clinical management.
Background:
Appropriate selection of robust assessment tools is essential to monitor physical function in children with cancer during and after treatment. This systematic review aims to identify and critically appraise the measurement properties of physical function measures currently used for children with cancer.
Procedure:
Two systematic searches of seven electronic databases [Cumulative Index to Nursing and Allied Health Literature (CINHAL), Medline, PubMed, PsychINFO, Sportsdiscus, EMBASE, and Allied and Complementary Medicine Database (AMED)] were completed to identify physical function measures used in children with cancer and to evaluate their measurement properties. Methodological quality and the adequacy of measurement properties specific to populations of children with cancer were critically appraised using the COSMIN framework to ascertain which measures have evidence to support their use in children with cancer.
Results:
One hundred and one physical function measures were identified across 154 studies. Measurement property data were available for 12 measures. The measurement properties of only two outcome measures were assessed in more than one study. Despite some positive measurement property data, there was no assessment tool that had consistent and adequate evidence overall to recommend its use in childhood cancer populations. Poor methodological quality of the included studies was the main limiting factor.
Conclusions:
There is very limited population specific evidence to guide the selection of physical function measures in children with cancer. Further research into the reliability, validity and responsiveness of physical function measures in children with cancer is needed to provide a basis for more effective clinical assessment and management.
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