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Effects of depression on heart rate variability in elderly patients with stable coronary artery disease
Ying Luo1, Shaomin Zhang2, Rongrong Zheng2
1Department of VIP Healthcare Management, West China Hospital, Sichuan University.
Insights
Depression significantly impacts heart rate variability (HRV) in elderly patients with coronary artery disease (CAD). Early evaluation of depression in CAD patients is crucial for managing HRV.
Area of Science:
- Cardiology
- Geriatrics
- Psychiatry
Background:
- Depression is a known independent risk factor for coronary artery disease (CAD).
- Understanding the relationship between depression and cardiac function is vital for patient outcomes.
Purpose of the Study:
- To evaluate the impact of depression on heart rate variability (HRV) in patients with stable CAD.
- To investigate the association between depression and HRV parameters in an elderly population.
Main Methods:
- Included 90 CAD patients with depression and 99 without, all with stable CAD.
- Utilized 24-hour Holter monitoring for HRV assessment.
- Depression was diagnosed using the 5-Item Geriatric Depression Scale.
Main Results:
- A linear correlation was observed between age and HRV.
- No significant HRV differences were found based on sex, marital status, or lifestyle factors (smoking, drinking).
- Multiple regression analysis confirmed a correlation between depression and HRV; beta-blockers affected specific HRV metrics.
Conclusions:
- Depression is a significant risk factor influencing HRV in elderly patients with CAD.
- Clinical attention to depressive symptoms in CAD patients is recommended for comprehensive care.
Background:
Depression is an independent risk factor in coronary artery disease (CAD). Our objective was to evaluate the impact of depression on heart rate variability (HRV) in patients with stable CAD.
Methods:
This study included patients with a stable CAD who admitted to our hospital in the geriatric medical center from August 2016 to December 2016. All patients agreed to participate in the study and sign informed consent. The study group included 90 CAD patients with a diagnosis of depression and 99 CAD patients without depression. All study population underwent a 24-hour Holter recording for HRV. The depression was assessed by 5-Item Geriatric Depression.
Results:
There was a linear correlation between age and HRV. There were no significant differences in heart rate variability between male and female patients, married and unmarried/widowed, smoking and nonsmoking, drinking and nondrinking groups. Multiple linear regression analysis showed that there were correlations between depression and HRV. β-blockers were associated with SDNN, SDANN, SDNN index, and RMSSD in HRV.
Conclusion:
Depression is an important risk factor for heart rate variability in elderly patients with CAD. Clinicians should pay attention for evaluation of depressive patients with CAD.
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