Spontaneous Coronary Artery Dissection and Hypothyroidism
Santiago Jesús Camacho Freire1, José Francisco Díaz Fernández1, Livia Luciana Gheorghe1
1Servicio de Cardiología, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.
Revista Espanola De Cardiologia (English Ed.)
|August 12, 2018
Summary
Hypothyroidism is common in spontaneous coronary artery dissection (SCAD) patients. Those with SCAD and hypothyroidism are typically women with dissections in distal, tortuous vessels, often managed conservatively.
Area of Science:
- Cardiology
- Endocrinology
- Vascular Medicine
Background:
- Thyroid hormone influences systemic metabolism.
- Spontaneous coronary artery dissection (SCAD) is a condition affecting coronary arteries.
- Thyroid disorders may impact cardiovascular health.
Purpose of the Study:
- To determine the prevalence of thyroid disorders in SCAD patients.
- To investigate the clinical characteristics and outcomes of SCAD patients with thyroid dysfunction.
Main Methods:
- Analysis of 73 consecutive SCAD patients.
- Comparison of baseline characteristics and outcomes between euthyroid and hypothyroid SCAD patients.
- Comparison of SCAD patients with hypothyroidism to matched acute coronary syndrome patients without SCAD.
Main Results:
- 26% of SCAD patients had hypothyroidism.
- SCAD patients with hypothyroidism were predominantly women (100%) and had dissections in distal, tortuous coronary segments.
- Hypothyroidism was more prevalent in SCAD patients (26%) compared to non-SCAD acute coronary syndrome patients (8%).
Conclusions:
- Hypothyroidism is highly prevalent in SCAD patients.
- SCAD patients with hypothyroidism often present with specific vessel characteristics and are managed conservatively.
- Thyroid function assessment is important in SCAD evaluation.
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