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Related Concept Videos

Design Example: Strain Gauge Bridge or Wheatstone Bridge01:15

Design Example: Strain Gauge Bridge or Wheatstone Bridge

1.0K
The utilization of strain gauges as transducers for converting mechanical strain into electrical signals is a common practice in various engineering applications. These strain gauges are frequently integrated into Wheatstone bridge circuits to accurately measure parameters such as force or pressure. Within this context, each element within the circuit exhibits a resistance that undergoes subtle variations when subjected to mechanical strain. The primary objective is to convert minuscule...
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Wheatstone Bridge01:29

Wheatstone Bridge

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An ohmmeter is a resistance-measuring device. It works by applying a voltage to a resistor of unknown resistance and measuring the current across the resistor. The resistance value is deduced using Ohm's law. Usually, the standard configuration of an ohmmeter comprises a voltmeter or an ammeter. However, such configurations are limited in accuracy because the meters alter the voltage applied to the resistor and the current that flows through it.
Thus, for accurate resistance measurements, a...
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Bridge rectifier01:24

Bridge rectifier

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The bridge rectifier is essential in electronics for efficiently converting alternating current (AC) to direct current (DC). Comprised of four diodes configured in a bridge layout, this rectifier effectively processes both the positive and negative halves of the AC waveform, making it superior to half-wave and full-wave center-tapped rectifiers in terms of voltage regulation and output stability.
Operationally, the bridge rectifier allows current flow through two of its diodes during each...
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Gap Junctions01:37

Gap Junctions

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Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
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Gap Junctions01:27

Gap Junctions

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The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
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Cross-bridge Cycle01:26

Cross-bridge Cycle

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As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
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Related Experiment Video

Updated: Feb 6, 2026

Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap
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Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap

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Glycomics@ExPASy: Bridging the Gap.

Julien Mariethoz1,2, Davide Alocci1,2, Alessandra Gastaldello1,2

  • 1From the ‡Proteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland.

Molecular & Cellular Proteomics : MCP
|August 12, 2018
PubMed
Summary

Glycomics@ExPASy centralizes glycoinformatics resources, offering user-friendly bioinformatics tools for glycoscientists and protein scientists. It aims to bridge glycobiology and protein data, facilitating research and hypothesis building.

Keywords:
BioinformaticsBioinformatics softwareGlycomicsGlycoproteomicsGlycosylation

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Glycan Node Analysis: A Bottom-up Approach to Glycomics
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Glycan Node Analysis: A Bottom-up Approach to Glycomics

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Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments
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Glycan Node Analysis: A Bottom-up Approach to Glycomics
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Area of Science:

  • Bioinformatics
  • Glycomics
  • Glycobiology

Background:

  • Glycomics@ExPASy, established in 2016 by the SIB Swiss Institute of Bioinformatics, centralizes glycoinformatics resources.
  • It hosts databases and tools developed by an international network of glycoscientists.

Purpose of the Study:

  • To popularize bioinformatics applications in glycobiology.
  • To highlight the connections between glycobiology and protein bioinformatics.
  • To facilitate data exploration and hypothesis generation by bridging these disciplines.

Main Methods:

  • Centralizing web-based glycoinformatics resources.
  • Developing interactive tools with database connectivity.
  • Collaborating with glycoscientists for community needs.

Main Results:

  • A comprehensive collection of glycoinformatics databases and tools.
  • Interactive resources designed for both glycoscientists and protein scientists.
  • Facilitation of data exploration and hypothesis building.

Conclusions:

  • Glycomics@ExPASy serves as a vital hub for glycoinformatics.
  • The platform promotes interdisciplinary research between glycobiology and protein science.
  • It addresses the growing need for integrated glycoinformatics resources.