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Nonpharmacological Interventions for Sleep Promotion on Preterm Infants in Neonatal Intensive Care Unit: A Systematic
Jin-Hua Liao1, Rong-Fang Hu1, Li-Jing Su1
1School of Nursing, Fujian Medical University, Fujian, China.
Insights
Nonpharmacological interventions like remolding mattresses and cycled light show promise for improving sleep in preterm infants in the NICU. However, current evidence quality is low, necessitating further research.
Area of Science:
- Neonatal Intensive Care Unit (NICU) care
- Pediatric sleep medicine
- Evidence-based practice in neonatology
Background:
- Nonpharmacological interventions are commonly employed to enhance sleep in preterm infants within the NICU setting.
- A comprehensive synthesis of existing evidence regarding the efficacy of these interventions is lacking.
Purpose of the Study:
- To systematically review and synthesize the evidence on the effectiveness of nonpharmacological interventions for improving sleep in preterm infants during their NICU stay.
Main Methods:
- A systematic literature search was conducted across seven major databases up to August 2017.
- Included studies were randomized controlled trials investigating nonpharmacological interventions for preterm infants' sleep.
- A meta-analysis was performed on data from 36 included studies.
Main Results:
- Remolding mattresses significantly improved total sleep time efficiency and active sleep efficiency.
- Cycled light interventions were found to increase total sleep time.
- Newborn Individualized Developmental Care and Assessment Program (NIDCAP) and cobedding showed no significant effects on sleep parameters.
Conclusions:
- Remolding mattresses and cycled light demonstrate potential for promoting sleep in preterm infants.
- The overall quality of the evidence supporting these interventions is very low.
- High-quality research is crucial to validate and strengthen the findings on sleep promotion strategies for NICU preterm infants.
Background:
Nonpharmacological interventions are often used to promote sleep among preterm infants in the neonatal intensive care unit (NICU). However, there is a lack of synthesis in the evidence of their effectiveness.
Aim:
To synthesize the evidence on the effectiveness of nonpharmacological interventions on NICU preterm infants' sleep during hospital stay.
Methods:
Seven databases were searched, including MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Wan-fang database, China National Knowledge Infrastructure, China Biological Medicine Database, and VIP Journal Integration Platform from their inceptions to August 2017. Randomized controlled trials examining the effects of nonpharmacological interventions on preterm infants' sleep were included.
Results:
This review included 36 studies. Nonpharmacological interventions included the Newborn Individualized Developmental Care and Assessment Program (NIDCAP), music, non-nutritive sucking, touch, cycled light, cobedding, rocking, oral sucrose, remolding mattresses, and family nurturing. The meta-analysis results showed that 1. the NIDCAP had no significant effect on total sleep time efficiency (TST%; p = .34); 2. mattress interventions had significant effects on TST% (p < .001); and active sleep efficiency (AS%; p = .006) but no significant effect on quiet sleep efficiency (QS%; p = .75); 3. cycled light increased TST (p = .02); and 4. cobedding had no significant effects on QS% and AS% (p = .63 and p = .88, respectively).
Linking Evidence To Action:
Remolding mattresses and cycled light had significant effects on sleep promotion in preterm infants, but the quality of the evidence was very low. Further high-quality studies are needed to strengthen this evidence.
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