Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

No serological association between Porphyromonas gingivalis or Prevotella intermedia and early spondyloarthritis: analysis from the DESIR cohort.

Clinical and experimental medicine·2026
Same author

Postmenopausal Osteoporosis, Endothelial Dysfunction, and Cardiovascular Risk.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same author

Dietary bioactive compounds modulating satiety and appetite: mechanisms of action.

Journal of physiology and biochemistry·2026
Same author

Bacterial translocation and intestinal permeability in early axial spondyloarthritis association with 5-year outcomes: insights from the DESIR cohort.

Rheumatology (Oxford, England)·2026
Same author

Longitudinal incidence of native septic arthritis in France: a 13-year analysis of the National Health Data System Database.

Rheumatology (Oxford, England)·2026
Same author

Multi-omics characterisation of the virulence and inflammatory potential of Bacillus thuringiensis in an in vitro intestinal epithelial model.

The Science of the total environment·2026

Related Experiment Video

Updated: Feb 6, 2026

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome
07:16

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome

Published on: March 4, 2016

17.7K

Sarcopenia.

Anne Tournadre1, Gaelle Vial1, Frédéric Capel2

  • 1Service de rhumatologie, CHU Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France; Unité de Nutrition Humaine, UMR1019 INRA, université Clermont-Auvergne, 63000 Clermont-Ferrand, France.

Joint Bone Spine
|August 12, 2018
PubMed
Summary

Sarcopenia, characterized by low muscle mass and function, affects aging individuals and those with chronic diseases. Management involves nutrition, exercise, and potential new therapies to combat its severe health impacts.

Keywords:
Fat massMuscleSarcopenia

More Related Videos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

11.8K
A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle
09:19

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle

Published on: May 26, 2022

4.8K

Related Experiment Videos

Last Updated: Feb 6, 2026

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome
07:16

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome

Published on: March 4, 2016

17.7K
Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

11.8K
A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle
09:19

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle

Published on: May 26, 2022

4.8K

Area of Science:

  • Gerontology
  • Muscle Physiology
  • Clinical Medicine

Background:

  • Sarcopenia is defined by low muscle mass and function, often associated with aging.
  • Causes include chronic disease, inactivity, and malnutrition, distinct from cachexia.
  • It involves complex mechanisms like inflammation, insulin resistance, and oxidative stress.

Purpose of the Study:

  • To define sarcopenia and its associated factors.
  • To outline its prevalence and consequences.
  • To discuss diagnostic and management strategies.

Main Methods:

  • Diagnosis relies on muscle mass assessment and functional tests (strength, performance).
  • No specific biomarkers are currently identified.
  • Research is exploring novel anabolic agents.

Main Results:

  • Prevalence varies (3-24%) and increases with age.
  • In rheumatoid arthritis, 20-30% have sarcopenia, correlating with disease severity.
  • Sarcopenia leads to disability, falls, metabolic disorders, and increased mortality.

Conclusions:

  • Sarcopenia significantly impairs quality of life and increases health risks.
  • Sarcopenic obesity presents unique challenges.
  • Multimodal management is crucial, with ongoing research into muscle anabolism stimulators.