Related Experiment Video
Updated: Feb 6, 2026

A Toxicological and Ecotoxicological Assay Based on Mussel (Mytilus galloprovincialis) Hemocytes Motility
Published on: December 13, 2024
Effects of low concentrations copper on antioxidant responses, DNA damage and genotoxicity in thick shell mussel
Kaida Xu1, Zurong Tang2, Shuobo Liu2
1Key Laboratory of Sustainable Utilization of Technology Research, Scientific Observing and Experimental Station of Fishery Resources for Key Fishing Grounds, MOA, Marine Fisheries Research Institute of Zhejiang, Zhejiang, Zhoushan, 316021, China.
Abstract:
For the aim to study potential detrimental effects induced by Cu exposure at low, environmentally relevant concentrations, the in vivo activities at different levels of biological organisations of thick shell mussel Mytilus coruscus exposed to two levels of copper were assessed. Cu-induced stresses were evaluated through antioxidant responses, DNA damage and genotoxicity. The results revealed significant higher SOD and CAT activities, and MDA concentration in haemocytes of M. coruscus with Cu exposure at 8 μg/L, while only significant accumulation in CAT activity with Cu exposure at 2 μg/L and no significant changes with SOD activity and MDA concentration at this level of Cu exposure. Copper exposure induced DNA damage as induction of OTM value in a time- and concentration-dependent manner. In addition, copper exposure could significantly induced the expressions of MT-10, Hsp70, Hsp90 and C3. The present results deepen the mussels as a suitable model marine invertebrate species to study potential detrimental effects induced by possible toxicants, in combinations at different levels of biological organisations.
Related Concept Videos
Radical Reactivity: Concentration Effects
DNA Damage Can Stall the Cell Cycle
DNA Damage can Stall the Cell Cycle
Concentration Cells
Consider the following voltaic cell:
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...
Solution Concentration and Dilution

