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Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
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Linalool bioactive properties and potential applicability in drug delivery systems.
Irina Pereira1, Patrícia Severino2, Ana C Santos3
1Faculty of Pharmacy, University of Coimbra (FFUC), Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal; University of Trás-os Montes e Alto Douro, UTAD, Quinta de Prados, P-5001-801 Vila Real, Portugal.
Colloids and Surfaces. B, Biointerfaces
|August 12, 2018
Summary
Linalool, a compound from essential oils, shows significant anti-inflammatory, anticancer, and neuroprotective effects. Nanotechnology can enhance these medicinal properties for pharmaceutical and cosmetic use.
Area of Science:
- Natural Product Chemistry
- Pharmacology
- Nanotechnology
Background:
- Essential oils from aromatic plants possess historical medicinal value.
- Technological advancements facilitate the extraction and identification of bioactive compounds like terpenes from essential oils.
- Linalool (C10H18O), a monoterpene alcohol, is a primary component in oils from plants such as lavender and coriander.
Purpose of the Study:
- To review the diverse bioactive properties of linalool.
- To explore the potential of linalool in pharmaceutical and cosmetic applications.
- To discuss the enhancement of linalool's properties through nanotechnology-based drug delivery systems.
Main Methods:
- Literature review of in vitro and in vivo scientific studies on linalool.
- Analysis of chemical structure and properties of linalool.
- Exploration of nanotechnology applications for drug delivery.
Main Results:
- Linalool exhibits anti-inflammatory, anticancer, anti-hyperlipidemic, antimicrobial, antinoceptive, analgesic, anxiolytic, antidepressive, and neuroprotective activities.
- Linalool is non-toxic and demonstrates broad bioactivity.
- Nanotechnology offers a method to improve the efficacy of linalool.
Conclusions:
- Linalool possesses a wide spectrum of therapeutic properties.
- Its non-toxic nature and diverse bioactivities make it a promising candidate for pharmaceutical and cosmetic development.
- Nanotechnology-based delivery systems can significantly enhance the therapeutic potential of linalool.
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