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Updated: Feb 6, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Gastrinomas: Medical or Surgical Treatment
Jeffrey A Norton1, Deshka S Foster1, Tetsuhide Ito2
1Department of Surgery, Stanford University School of Medicine, 291 campus Drive, Stanford, CA 94305-5101, USA.
Abstract:
This article reviews the role of surgical and medical management in patients with Zollinger-Ellison syndrome (ZES) due to a gastrin-secreting neuroendocrine tumor (gastrinoma). It concentrates on the status at present but also briefly reviews the changes over time in treatment approaches. Generally, surgical and medical therapy are complementary today; however, in some cases, such as patients with ZES and multiple endocrine neoplasia type 1, the treatment approach remains controversial.
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