Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Force Classification01:22

Force Classification

2.4K
Forces play a crucial role in the study of physics and engineering. They are essential in describing the motion, behavior, and equilibrium of objects in the physical world. Forces can be classified based on their origin, type, and direction of action.
Contact and non-contact forces are two of the most widely used categories of forces. As the name suggests, contact forces require physical contact between two objects to act upon each other. Examples of contact forces include frictional,...
2.4K
Classification of Neurotransmitters01:30

Classification of Neurotransmitters

5.3K
Neurotransmitters play a crucial role in the communication between neurons in the autonomic nervous system. Neurons in the autonomic nervous system can be cholinergic or adrenergic depending on the neurotransmitters synthesized. Cholinergic neurons use acetylcholine as their primary neurotransmitter. This includes all the preganglionic fibers of the sympathetic and pre- and postganglionic fibers of the parasympathetic nervous systems. In addition, neurons of the somatic nervous system also use...
5.3K
Classification of Leukocytes01:30

Classification of Leukocytes

6.0K
Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
6.0K
Classification of Illness01:17

Classification of Illness

8.8K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
8.8K
Classification of Bones01:18

Classification of Bones

10.0K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
10.0K
Seizures: Classification01:13

Seizures: Classification

1.6K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Executive anosognosia in progressive supranuclear palsy versus Parkinson's disease.

Frontiers in neurology·2026
Same author

[18F]fluorodeprenyl-D2 PET can detect and monitor astrogliosis in anti-LGI1-IgG autoimmune encephalitis.

European journal of nuclear medicine and molecular imaging·2025
Same author

Recurrent infarcts from thyroid cartilage compression of an aberrant vertebral artery: rare, easily overlooked, but treatable.

Journal of neurology·2023
Same author

Disease modification in Parkinsonism: obstacles and ways forward.

Journal of neural transmission (Vienna, Austria : 1996)·2022
Same author

Drug safety profiles in geriatric patients with Parkinson's disease using the FORTA (Fit fOR The Aged) classification: results from a mono-centric retrospective analysis.

Journal of neural transmission (Vienna, Austria : 1996)·2020
Same author

Argyrophilic grain disease in individuals younger than 75 years: clinical variability in an under-recognized limbic tauopathy.

European journal of neurology·2020

Related Experiment Video

Updated: Feb 6, 2026

Flying Insect Detection and Classification with Inexpensive Sensors
05:16

Flying Insect Detection and Classification with Inexpensive Sensors

Published on: October 15, 2014

25.7K

New classification of tauopathies.

G U Höglinger1, G Respondek1, G G Kovacs2

  • 1German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, D-81377 Munich, Germany; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Revue Neurologique
|August 13, 2018
PubMed
Summary

Tauopathies are neurodegenerative diseases linked to abnormal tau protein deposits. Molecular classification is key for developing targeted therapies beyond symptom management.

Keywords:
Corticobasal degenerationCorticobasal syndromeProgressive supranuclear palsyRichardson's syndromeTauopathies

More Related Videos

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.5K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

8.1K

Related Experiment Videos

Last Updated: Feb 6, 2026

Flying Insect Detection and Classification with Inexpensive Sensors
05:16

Flying Insect Detection and Classification with Inexpensive Sensors

Published on: October 15, 2014

25.7K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.5K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

8.1K

Area of Science:

  • Neuroscience
  • Neuropathology

Background:

  • Tauopathies encompass diverse neurodegenerative diseases defined by pathological tau protein accumulation within cells.
  • These conditions present with varied clinical symptoms, including motor and cognitive dysfunction.
  • Current understanding distinguishes tauopathies based on tau protein's molecular characteristics.

Purpose of the Study:

  • To highlight the importance of molecular pathological classification in understanding tauopathies.
  • To differentiate between syndrome-based and molecular-pathological classifications.
  • To emphasize the role of molecular classification in developing disease-modifying therapies.

Main Methods:

  • Review of existing literature on tauopathies.
  • Analysis of molecular and pathological features defining distinct tauopathies.
  • Comparison of clinical and molecular classification systems.

Main Results:

  • Distinct tauopathies are defined by specific tau protein isoform composition, morphology, and distribution.
  • Tauopathies manifest clinically with either primary motor or cognitive symptoms.
  • Molecular-pathological classification complements traditional syndrome-based approaches.

Conclusions:

  • Molecular pathological classification is crucial for identifying distinct tauopathy entities.
  • This classification is essential for the development of targeted, disease-modifying therapies.
  • While syndrome-based classification aids symptomatic treatment, molecular insights drive therapeutic innovation.