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Germ Cell-Specific Retinoic Acid Receptor α Functions in Germ Cell Organization, Meiotic Integrity, and Spermatogonia

Natalie R Peer1, Sze Ming Law1, Brenda Murdoch1,2

  • 1School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington.

Endocrinology
|August 13, 2018
PubMed
Summary

Retinoic acid receptor alpha (RARA) in male germ cells is crucial for sperm production and testicular organization. Its absence impairs meiosis, spermatogonial proliferation, and overall male fertility.

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