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Urine therapy in Ayurveda: Ancient insights to modern discoveries for cancer regression
1Medical Research Centre, Kasturba Health Society, Vile Parle (W), Mumbai, 400056, Maharashtra, India.
Abstract:
Investigation of spontaneous regressions (SR) of cancer may explain host mechanisms of control by anticancer substance (A.C.S.). Documented human SR, of bladder cancer after uretero-sigmoidostomy and of uterine leiomyosarcoma after irreparable vesico-vaginal fistula, suggested the presence of A.C.S. in human urine. Animal experiments with urine in rat alveolar carcinoma and in mouse melanoma point to A.C.S. Urine therapy, as cited in Bhrigu-Samhita and used in some cases, needs to be followed up by systematic Reverse Pharmacology and analytical identification of A.C.S.
Insights
Investigating spontaneous cancer regressions suggests a host control mechanism involving an anticancer substance (ACS). Human and animal studies indicate this ACS may be present in urine, warranting further research.
Area of Science:
- Oncology
- Immunology
- Pharmacology
Background:
- Spontaneous regressions (SR) of cancer offer insights into host-mediated anticancer mechanisms.
- Previous observations in bladder cancer and uterine leiomyosarcoma suggested the presence of an anticancer substance (ACS) in human urine.
- Traditional practices like urine therapy, mentioned in ancient texts, hint at potential therapeutic properties of urine.
Purpose of the Study:
- To investigate the potential role of an anticancer substance (ACS) in spontaneous cancer regressions.
- To explore the presence and source of ACS in human and animal urine.
- To provide a scientific basis for traditional urine therapy through reverse pharmacology.
Main Methods:
- Review of documented cases of spontaneous cancer regression in humans.
- Animal experiments involving the administration of urine to induce tumor regression in rats and mice.
- Application of reverse pharmacology principles to analyze urine composition.
Main Results:
- Human cases of spontaneous regression in bladder cancer and uterine leiomyosarcoma indirectly suggest the presence of ACS in urine.
- Animal studies demonstrated a potential anticancer effect of urine in rat alveolar carcinoma and mouse melanoma models.
- Evidence supports the hypothesis that urine contains a substance with anticancer properties.
Conclusions:
- Spontaneous cancer regressions may be mediated by an endogenous anticancer substance (ACS).
- Human and animal urine appears to contain ACS, suggesting a potential therapeutic agent.
- Further systematic research, including analytical identification of ACS, is needed to validate urine therapy and develop novel cancer treatments.
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