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Related Concept Videos

Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

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The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
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Adrenal Gland Disorders01:27

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Updated: Feb 6, 2026

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
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[Bilateral adrenal tuberculosis: about a case].

Nawal Bouknani1, Daoud Bentaleb1, Hasna Belgadir1

  • 1Service de Radiologie 20 Aout 1953, CHU Ibn Rochd de Casablanca, Casablanca, Maroc.

The Pan African Medical Journal
|August 14, 2018
PubMed
Summary
This summary is machine-generated.

Adrenal tuberculosis, a rare cause of adrenal insufficiency, presents subtly. Early diagnosis and treatment with anti-tubercular therapy led to significant clinical improvement in a patient with adrenal incidentaloma.

Keywords:
Adrenal tuberculosisCT scanimagingincidentaloma

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Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Radiology

Background:

  • Isolated adrenal tuberculosis is an uncommon cause of adrenal incidentalomas, representing less than 2% of cases.
  • It is recognized as the most frequent infectious etiology of adrenal insufficiency.

Observation:

  • A 53-year-old patient with no prior medical history presented with a six-month history of gradually worsening adrenal insufficiency.
  • Physical examination revealed no masses or hepatosplenomegaly. Blood pressure was 120/60 mmHg.
  • CT scan demonstrated bilateral adrenal gland hypertrophy with calcifications. Intradermal tuberculin reaction was positive (25mm), and Quantiferon® test was positive, while sputum and urine tests for Mycobacterium tuberculosis were negative.

Findings:

  • The patient exhibited low hormonal assays consistent with adrenal insufficiency.
  • A trial of anti-bacillary treatment resulted in clinical improvement, including a 5kg weight gain over 12 months.

Implications:

  • This case highlights the importance of considering adrenal tuberculosis in the differential diagnosis of adrenal insufficiency, even with negative microbiological tests.
  • Prompt initiation of anti-tubercular treatment can lead to favorable outcomes and reversal of adrenal insufficiency symptoms.