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Updated: Feb 6, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation for atrial fibrillation: current patient selection and outcomes
Katie Walsh1, Francis Marchlinski1
1a Cardiac Electrophysiology Section, Cardiovascular Division , Hospital of University of Pennsylvania , Philadelphia , PA , USA.
Introduction:
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Ablation is an excellent treatment option for appropriately selected patients. Catheter ablation tools and techniques have evolved since AF ablation was first introduced, but pulmonary vein isolation remains the cornerstone of the procedure. Outcomes from ablation have improved dramatically over the last 20 years, but remain less than optimal for certain patient groups. Areas covered: This review outlines the process of patient selection for AF ablation in contemporary practice, from diagnosis and AF classification to procedural risk assessment. Current guideline indications for AF ablation are reviewed. We discuss current reported outcomes from AF ablation and predictors for arrhythmia recurrence after ablation. The evolution of AF ablation technology and change in patient selection patterns are also discussed. Expert commentary: AF ablation is an attractive alternative to antiarrhythmic drug therapy for many patients. Patient selection for ablation is an important part of management. Careful patient selection requires thorough, individualized clinical assessment based on symptoms, alternative treatment options, an estimation of procedural risk, and predicted recurrence rate to allow the patient to participate in shared decision-making.
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