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Updated: Feb 6, 2026

Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head
Published on: January 3, 2020
Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems
Taku Sugawa1, Takaaki Murakami1, Daisuke Yabe1
1Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Abstract:
The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.
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