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Updated: Feb 6, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
Syntheses, structures and magnetic properties of macrocyclic Schiff base-supported homodinuclear lanthanide complexes
Feng Gao1, Yi-Quan Zhang, Wang Sun
1School of Chemistry & Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. gf2016@jsnu.edu.cn.
Abstract:
Five new homodinuclear lanthanide complexes with the general formula [(acac)4Ln2(L)] (Ln3+ = Dy3+ (1), Tb3+ (2), Ho3+ (3), Er3+ (4), and Gd (5)) were synthesized by one-pot [2 + 2] condensation of 2,6-diformyl-4-methylphenol and 1,3-diaminopropane in the presence of various lanthanide acetylacetonates. The eight-coordinate Ln(iii) centre adopts a slightly distorted square antiprism geometry with D4d symmetry. Theoretical analysis and magnetic measurements reveal that the corresponding Dy complex 1 exhibits slow magnetic relaxation behavior, characteristic of a typical SMM with the intramolecular ferromagnetic Dy3+Dy3+ interaction.
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