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Huntington's Disease Clinical Trials Corner: August 2018
Filipe B Rodrigues1,2,3, Edward J Wild1
1Huntington's Disease Centre, University College London, UK.
Journal of Huntington'S Disease
|August 15, 2018
Summary
This review details ongoing Huntington's Disease clinical trials, including updates on the SIGNAL and CREST-E studies. It provides a comprehensive overview of current research in Huntington's Disease therapeutics.
Area of Science:
- Neuroscience
- Genetics
- Clinical Research
Background:
- Huntington's Disease (HD) is a progressive neurodegenerative disorder.
- Effective treatments are limited, necessitating ongoing clinical trial research.
- Understanding the landscape of ongoing trials is crucial for patients and researchers.
Purpose of the Study:
- To provide an updated overview of registered and ongoing clinical trials for Huntington's Disease.
- To offer detailed insights into specific trials, such as the SIGNAL study (NCT02481674).
- To summarize findings from recently completed trials, like the CREST-E study (NCT00712426).
Main Methods:
- Systematic review of clinical trial registries.
- In-depth analysis of selected ongoing and completed Huntington's Disease trials.
- Compilation and summarization of trial information and outcomes.
Main Results:
- A comprehensive list of current Huntington's Disease clinical trials is presented.
- Key aspects and progress of the SIGNAL trial are elaborated.
- Outcomes and conclusions from the CREST-E trial are discussed.
Conclusions:
- The review highlights the active research efforts in Huntington's Disease.
- It serves as a valuable resource for tracking therapeutic development in HD.
- Continued investigation through clinical trials is essential for advancing Huntington's Disease treatment.