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Imaging Protocols for Active Surveillance in Renal Cell Carcinoma
Christine W Liaw1, Jared S Winoker1, Reza Mehrazin2
1Department of Urology at the Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place, New York, NY, 10029, USA.
Active surveillance for small renal masses lacks standardized imaging protocols, despite its acceptance for high-risk patients. Current guidelines offer broad recommendations, necessitating further research into optimal follow-up strategies.
Area of Science:
- Urology
- Oncology
- Radiology
Background:
- Small renal masses (SRMs) are increasingly detected, necessitating clear management guidelines.
- Active surveillance is a viable option for SRMs, particularly in patients with surgical contraindications.
Purpose of the Study:
- To review SRM growth kinetics and imaging modalities.
- To highlight current organizational recommendations for active surveillance of SRMs.
- To discuss oncological outcomes related to surveillance protocols and delayed intervention.
Main Methods:
- Literature review of growth kinetics, imaging, and surveillance guidelines for SRMs.
- Analysis of recent oncological outcomes and progression to intervention.
Main Results:
- Organizational guidelines for SRM surveillance imaging lack specific timing and modality recommendations.
- While criteria for intervention exist, formal guidelines are absent.
- Standardized imaging protocols and prospective trials for SRM surveillance are lacking.
Conclusions:
- Active surveillance is an acceptable strategy for SRMs in high-risk patients.
- There is a need for standardized imaging protocols and further research to optimize SRM surveillance.
- Current guidelines are broad, underscoring the need for more specific recommendations.
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