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Published on: December 29, 2016
Synthesis and Reactivity of N-Allenyl Cyanamides
James N Ayres1, Matthew T J Williams1, Graham J Tizzard2
1School of Chemistry , Cardiff University , Main Building, Park Place , Cardiff CF10 3AT , U.K.
Abstract:
N-Allenyl cyanamides have been accessed via a one-pot deoxycyanamidation-isomerization approach using propargyl alcohol and N-cyano- N-phenyl- p-methylbenzenesulfonamide. The utility of this novel class of allenamide was explored through derivatization, with hydroarylation, hydroamination, and cycloaddition protocols employed to access an array of cyanamide products that would be challenging to access using existing methods.
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