Author Correction: Cryo-EM structure of a fungal mitochondrial calcium uniporter

Nam X Nguyen1,2, Jean-Paul Armache3, Changkeun Lee1,2,4

  • 1Howard Hughes Medical Institute and Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature
|August 16, 2018
PubMed

Insights

This study involved minor reference updates for accuracy. The article now includes a replaced reference and renumbered citations for improved scholarly integrity.

Area of Science:

  • Structural Biology and high-resolution Cryo-Electron Microscopy.
  • Mitochondrial Physiology and the fungal mitochondrial calcium uniporter.

Background:

Scientific publishing requires rigorous adherence to citation standards to maintain the integrity of the scholarly record. Prior research has shown that accurate bibliographic data allows researchers to trace the development of structural models and experimental protocols effectively. In the context of high-resolution imaging, the precise attribution of previous findings regarding mitochondrial transport proteins is essential for contextualizing new structural data. The original publication regarding the fungal mitochondrial calcium uniporter contained specific errors in its reference list that required formal amendment to ensure clarity. Maintaining a clear and error-free connection between current findings and established literature ensures that the scientific community can verify the evidence base. This absence of evidence motivated the editorial team and the authors to issue a formal correction to the online version of the article.

Purpose Of The Study:

The primary objective of this formal amendment involves the rectification of specific bibliographic inaccuracies within the original manuscript. The authors sought to replace reference 15 to ensure that the cited work accurately reflects the intended scientific context of the study. This effort also aimed to renumber references 32 through 50 to maintain a logical and sequential flow throughout the online text. Correcting these citations is necessary to prevent confusion among readers who are examining the structural details of the mitochondrial calcium transport system. By updating the digital record, the researchers ensure that the scholarly lineage of the fungal mitochondrial calcium uniporter remains transparent and verifiable. This effort focuses on upholding the high standards of accuracy expected in structural biology publications and digital archives.

Main Methods:

The investigative process for this correction involved a comprehensive review of the citation list associated with the Cryo-EM structure. The editorial staff and authors identified that reference 15 required immediate replacement with a more appropriate or accurate source for the reported data. Subsequently, a systematic renumbering protocol was applied to the references spanning from 32 to 50 in the online version of the article. This digital adjustment ensures that every citation within the text corresponds correctly to the final bibliography provided at the end of the paper. The researchers utilized the journal's online publishing platform to implement these changes across the entire document, ensuring that the digital record remains consistent. These specific technical steps were taken to preserve the utility of the reference list for the global scientific community.

Main Results:

The primary result of this action is the successful replacement of reference 15 within the corrected version of the manuscript. The online text now features a renumbered sequence for references 32 through 50, ensuring bibliographic consistency across the entire report. These modifications allow for a seamless reading experience where the citations align perfectly with the supporting evidence for the fungal mitochondrial calcium uniporter structure. The structural data obtained through Cryo-EM remains unchanged and continues to provide a high-resolution view of the mitochondrial calcium uniporter. No alterations were made to the primary experimental findings or the structural models presented in the original report. The correction successfully addresses the identified clerical errors without impacting the scientific conclusions regarding fungal mitochondrial physiology.

Conclusions:

The authors conclude that the updated reference list provides a more accurate and reliable foundation for the reported structural findings. These bibliographic corrections are essential for researchers who rely on the fungal mitochondrial calcium uniporter data for subsequent studies in mitochondrial biology. By ensuring that reference 15 and the sequence from 32 to 50 are correct, the authors maintain the trustworthiness of the published record. Future investigations into the mechanism of calcium transport can now proceed with a clear understanding of the relevant literature. The researchers emphasize that the integrity of the Cryo-EM structure remains the focal point of the corrected article. This formal update serves as a necessary step in the ongoing process of scientific self-correction and documentation.

Frequently Asked Questions

Related Concept Videos

Milgram's Obedience to Authority02:20

Milgram's Obedience to Authority

Obedience to authority is classically demonstrated in a more famous series of social psychology experiments performed by Stanley Milgram. He was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. Eichmann’s defense for the atrocities he committed was that he was “just following orders.”
7.4K
Distance Corrections01:15

Distance Corrections

To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
293
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.3K
Power Factor Correction01:20

Power Factor Correction

The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
544
Interaction of EM Radiation with Matter: Spectroscopy01:12

Interaction of EM Radiation with Matter: Spectroscopy

Electromagnetic (EM) radiation can be considered an oscillating electric and magnetic field propagating through a medium that can interact with matter in its path. The electric field in the radiation can interact with electrical charges in the atoms or molecules in the matter. On the other hand, the magnetic field can interact with the magnetic field in the atomic nucleus. The study of the interaction between electromagnetic radiation and matter is termed spectroscopy. Spectroscopy is the study...
3.3K
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
1.3K