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In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
Published on: September 7, 2022
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[Panuveitis of infectious genesis]
1Klinik für Augenheilkunde, Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
Summary
Ophthalmologists should consider infectious causes like syphilis and HIV when diagnosing eye inflammation. Early detection of panuveitis, papillitis, and chorioretinitis is crucial for patients with vision loss.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- Sub-acute vision loss can indicate serious intraocular inflammation.
- Syphilis (lues) and human immunodeficiency virus (HIV) infections are increasing.
- Ocular inflammation can be a presenting sign of systemic infections.
Purpose of the Study:
- To highlight the importance of considering infectious etiologies in cases of panuveitis.
- To emphasize the diagnostic challenge posed by co-infections like syphilis and HIV.
- To raise awareness among ophthalmologists regarding the rising incidence of these infections.
Main Methods:
- Case presentation of a patient with sub-acute vision loss.
- Diagnostic workup including ophthalmological examination.
- Review of epidemiological data on HIV and syphilis incidence.
Main Results:
- Diagnosis of panuveitis, papillitis, and chorioretinitis.
- Initial differential diagnosis included syphilis and HIV.
- Epidemiological trends support the relevance of these infectious agents.
Conclusions:
- Infectious etiologies, particularly syphilis and HIV, must be considered in patients presenting with panuveitis.
- Ophthalmologists should maintain a high index of suspicion for these infections.
- Prompt diagnosis and management are essential for vision preservation.
