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Updated: Feb 6, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
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Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Published on: August 1, 2018

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Bariatric Surgery in Patients with Cirrhosis and Portal Hypertension

Zubaidah Nor Hanipah1,2, Suriya Punchai1,3, Arthur McCullough4

  • 1Bariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, M61, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

Obesity Surgery
|August 16, 2018
PubMed

Insights

Bariatric surgery in patients with cirrhosis and portal hypertension is safe and effective, showing significant weight loss and comorbidity improvement. This study reviewed 13 such patients, finding minimal complications and positive outcomes.

Area of Science:

  • Gastroenterology
  • Bariatric Surgery
  • Hepatology

Background:

  • Limited studies exist on bariatric surgery outcomes in patients with cirrhosis and portal hypertension.
  • Portal hypertension is a serious complication of cirrhosis, affecting surgical risk.

Purpose of the Study:

  • To review the safety and effectiveness of bariatric surgery in cirrhotic patients with portal hypertension.
  • To evaluate short-term complications and long-term weight loss and comorbidity resolution.

Main Methods:

  • Retrospective review of cirrhotic patients with portal hypertension who underwent laparoscopic bariatric surgery between 2007 and 2017.
  • Data collected included patient demographics, surgical procedures, complications, weight loss, and comorbidity status.

Main Results:

  • Thirteen patients (8 female, median age 54) with median BMI 48 kg/m² underwent sleeve gastrectomy (77%) or Roux-en-Y gastric bypass (23%).
  • Three 30-day complications (wound infection, intra-abdominal hematoma, subcutaneous hematoma) occurred; no mortality. Median EWL and TWL at 2 years were 49% and 25%.
  • Significant improvements were observed in diabetes (100%), dyslipidemia (100%), and hypertension (50%) at 2-year follow-up.

Conclusions:

  • Bariatric surgery is relatively safe and effective in selected cirrhotic patients with portal hypertension.
  • The procedure leads to substantial weight loss and significant improvement in obesity-related comorbidities.
Abstract

Keywords:
Bariatric surgeryCirrhosisGastric bypassMorbidityMortalityPortal hypertensionRisk factorSleeve gastrectomy

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