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Could Probiotics Be Used to Mitigate Neuroinflammation?
Matthew G Frank1,2, Laura K Fonken3, Linda R Watkins1,2
1Department of Psychology and Neuroscience , University of Colorado Boulder , Boulder , Colorado 80309 , United States.
ACS Chemical Neuroscience
|August 16, 2018
Summary
Neuroinflammation impacts mood, motivation, and cognition. Probiotic treatments show promise for long-lasting immunoregulation in the central nervous system (CNS), potentially mitigating these negative effects.
Area of Science:
- Neuroscience
- Immunology
- Microbiology
Background:
- Neuroinflammation is linked to mood disorders, anhedonia, and cognitive decline.
- Current strategies focus on enhancing immunoregulatory processes, like increasing anti-inflammatory cytokines in the central nervous system (CNS).
Purpose of the Study:
- To explore the potential of probiotic treatments in managing neuroinflammation.
- To investigate if probiotics can induce long-lasting immunoregulation within the CNS.
Main Methods:
- Review of recent scientific evidence on probiotic interventions.
- Analysis of studies investigating the effects of probiotics on CNS immunoregulatory processes.
Main Results:
- Probiotic treatment may effectively induce long-lasting immunoregulation in the CNS.
- This immunoregulation has the potential to mitigate the adverse neural and behavioral effects of neuroinflammation.
Conclusions:
- Probiotics represent a promising therapeutic strategy for neuroinflammatory conditions.
- Further research is warranted to fully elucidate the mechanisms and efficacy of probiotics in CNS health.
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