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Updated: Feb 6, 2026

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
Published on: January 20, 2023
Rapid degradation of malachite green by CoFe2O4-SiC foam under microwave radiation
Yanpeng Mao1, Shanxiu Yang1, Chao Xue1
1National Engineering Laboratory of Coal-fired Pollutants Emission Reduction, School of Energy and Power Engineering, Shandong University, Jinan 250100, People's Republic of China.
Abstract:
This study demonstrated rapid degradation of malachite green (MG) by a microwave (MW)-induced enhanced catalytic process with CoFe2O4-SiC foam. The catalyst was synthesized from CoFe2O4 particles and SiC foam by the hydrothermal method. X-ray diffraction and scanning electron microscopy techniques were used to confirm that CoFe2O4 particles were settled on the surface of SiC foam. In this experiment, a novel fixed-bed reactor was set up with this catalyst for a continuous flow process in a MW oven. The different parameters that affect the MW-induced degradation rate of MG were explored. The MW irradiation leads to the effective catalytic degradation of MG, achieving 95.01% degradation within 5 min at pH 8.5. At the same time, the good stability and applicability of CoFe2O4-SiC foam for the degradation process were also discussed, as well as the underlying mechanism. In brief, these findings make the CoFe2O4-SiC foam an excellent catalyst that could be used in practical rapid degradation of MG.
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