Related Experiment Video
Updated: Feb 6, 2026

Step-by-Step Stapedotomy through Transcanal Exclusive Endoscopic Approach
Published on: March 5, 2022
Two golden times in two-step contagion models: A nonlinear map approach
Wonjun Choi1, Deokjae Lee1, J Kertész2,3
1CCSS, CTP and Department of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.
Pandemic outbreaks can be predicted using a two-step contagion model. Researchers discovered two distinct "golden times" for intervention, dependent on initial infection numbers and system size, offering new pandemic control strategies.
Area of Science:
- Epidemiology
- Network Science
- Mathematical Modeling
Background:
- The two-step contagion model simulates real-world pandemic outbreaks.
- It identifies a critical
- golden time
- for intervention before a pandemic occurs.
- Understanding how this time scales with system size is crucial for pandemic control.
Purpose of the Study:
- To investigate the size-dependence of
- golden time
- in the two-step contagion model.
- To identify different types of
- golden time
- and their scaling behaviors.
- To explore the universality and model-dependence of these scaling exponents.
Main Methods:
- Utilized a nonlinear mapping approach to analyze the two-step contagion model.
- Examined the scaling of
- golden time
- with system size N on Erdős-Rényi networks.
- Differentiated scaling behaviors based on the initial number of infected nodes.
Main Results:
- Identified two types of
- golden time
- , scaling as O(N^{1/3}) and O(N^{ζ}) (with ζ ≈ 1/4).
- The O(N^{1/3}) scaling is universal for models with discontinuous transitions.
- The ζ exponent shows model-dependence and its asymptotic behavior remains an open question.
Conclusions:
- The study reveals two distinct
- golden time
- regimes in the two-step contagion model.
- The findings provide insights into pandemic outbreak dynamics and control strategies.
- The nonlinear mapping method is applicable to other models exhibiting hybrid percolation transitions.
Related Concept Videos
Nonlinear Pharmacokinetics: Causes of Nonlinearity
Nonlinear drug absorption can occur when the process is rate-limited by solubility, carrier-mediated transport systems, or saturation of the presystemic gut wall or hepatic metabolism. For instance, high doses of riboflavin...
Steps in the Modeling Process
Attention is the first necessary component for observational learning. It involves focusing on what the model is doing and saying. For example, if you decide to take a drawing class to enhance your skills, you need to pay close attention to the instructor's words and hand movements. The characteristics of the model significantly...
Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model
When a drug is administered through a constant intravenous infusion and eliminated via nonlinear pharmacokinetics, it follows zero-order input. For example, oral drugs undergo first-order absorption upon administration and are eliminated through nonlinear pharmacokinetics.
In the case of subcutaneously administered drugs,...
Application of Nonlinear Inequalities
Introduction to Nonlinear Inequalities
Nonlinear Pharmacokinetics: Overview
Nonlinearity can arise due to the saturation of plasma protein-binding or...

