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Related Experiment Video

Updated: Feb 6, 2026

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
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Palliative Mastectomy Revisited.

Digpal V Dharkar1, Sonia Moses1

  • 1Indian Institute of Head and Neck Oncology, Indore Cancer Foundation, Indore, Madhya Pradesh, India.

Indian Journal of Palliative Care
|August 17, 2018
PubMed
Summary

Palliative mastectomy, once common for advanced breast cancer, remains a potent option in select cases. Achieving clear surgical margins and adequate depth is crucial for effective palliation.

Area of Science:

  • Oncology
  • Surgical Oncology

Background:

  • Palliative mastectomy was a frequent surgical procedure for locally advanced breast cancers.
  • Advances in tumor biology and multidisciplinary care have reduced its frequency.

Purpose of the Study:

  • To discuss the current role and essential technical aspects of palliative mastectomy for locally advanced breast cancer.

Main Methods:

  • Review of the indications and surgical considerations for palliative mastectomy.
  • Emphasis on achieving clear surgical margins and adequate tumor base clearance.

Main Results:

  • Palliative mastectomy is still a viable option for specific patient subsets with locally advanced breast cancer.
  • The procedure requires experienced breast cancer surgeons to ensure effective palliation.
Keywords:
Locally advanced breast cancerpalliative mastectomypatient selectionswift palliation

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Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
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Last Updated: Feb 6, 2026

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Conclusions:

  • While its role has diminished, palliative mastectomy remains important for selected patients.
  • Meticulous surgical technique focusing on margins and depth is paramount for successful outcomes.