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Ex vivo Live Imaging of Lung Metastasis and Their Microenvironment
Published on: February 3, 2016
Lung adenocarcinoma presenting with an orbital metastasis
Noni Novisari Soeroso1, Setia Putra Tarigan1, Wina Saragih1
1Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Jl. Dr. Mansyur No. 66, Medan, 20154, Sumatera Utara, Indonesia.
Abstract:
Orbital metastasis of lung adenocarcinoma is very rare. The incidence is only found to be approximately 7%-12% of lung cancer cases. The lack of knowledge about orbital metastasis results in misdiagnosis between malignant or benign lesion. This was a case of a 39-year-old woman complaining about a protruding left eye and a blind pain in the left eye characterized by hyperemesis eyeball. A CT scan of the orbital showed a soft tissue tumor in the fronto-naso-superomedial area of the left orbital with suspicion of infiltration of the medial rectus muscle, left bulbus oculi, lamina papyracea, and left frontal sinus wall which causes proptosis and soft tissue tumor in the left temporal region with suspicion of infiltration in the left sphenoid wing with an impression of metastasis. A Fine Needle Aspiration Biopsy (FNAB) in the temporal and intra-orbital region showed metastatic adenocarcinoma. Moreover, findings of the chest x-ray and chest CT scan concluded that there was a tumor in the left lung, and a bronchoscopy found adenocarcinoma as the biopsy results.
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