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[Progress on ionomics of complex diseases].

Hui-Min Ying1, Yan Zhang2

  • 1Department of Endocrinology, Hangzhou Xixi Hospital, Hangzhou 310023, China.

Sheng Li Xue Bao : [Acta Physiologica Sinica]
|August 17, 2018
PubMed
Summary

Ionomics, the study of element composition in biological systems, offers new insights into complex diseases. This field combines high-throughput measurement and bioinformatics for better understanding disease causes and treatments.

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Area of Science:

  • Ionomics: A multidisciplinary field integrating elemental analysis with biological systems.

Background:

  • Complex diseases involve intricate biological processes and elemental variations.
  • Understanding elemental composition is crucial for disease etiology and progression.

Purpose of the Study:

  • To review current advances in ionomic studies of complex diseases.
  • To highlight the role of elements and their networks in disease development.

Main Methods:

  • High-throughput techniques for element profile measurement.
  • Bioinformatic approaches for systems-level analysis.
  • Integration of elemental data with biological context.

Main Results:

  • Ionomics provides a systems-level understanding of elemental utilization and function.
  • Elemental profiles and networks are linked to physiological and pathological conditions.
  • Advances in ionomics offer insights into disease mechanisms.

Conclusions:

  • Ionomics holds significant theoretical and practical value for complex diseases.
  • It aids in etiological studies, early diagnosis, and therapeutic strategy selection.
  • Further understanding of elemental effects and ionomic networks is crucial.