Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Basic Concept

Basic Concept

Engineering mechanics is a branch of engineering that studies motion and the forces acting on objects. It is a fundamental subject and forms the basis of many other engineering disciplines. Length, time, mass, and force are some basic concepts in engineering mechanics.
Length, which measures the distance traveled by an object, is a fundamental concept in engineering mechanics. We use coordinates relative to a reference point to describe the distance. Length not only helps to describe the...

Automatic Processing and Automatic Social Behavior

Automatic Processing and Automatic Social Behavior

Automatic processing refers to the cognitive operations that occur without conscious intent or awareness, playing a fundamental role in shaping social cognition and behavior. These processes enable individuals to navigate complex social environments efficiently by relying on mental shortcuts and pre-existing knowledge structures known as schemas. One of the most influential mechanisms underlying automatic processing is priming, which subtly activates mental representations through exposure to...

Self-Concept

Self-Concept

Self-concept is the cognitive and emotional understanding individuals hold about their identity. It evolves through various developmental stages, beginning in infancy and maturing as children grow. This concept influences how individuals perceive their abilities, interact with others, and manage challenges throughout life.
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...

Energy Basics

Energy Basics

Chemical reactions, such as those that occur when you light a match, involve changes in energy as well as matter.

Concepts and Prototypes

Concepts and Prototypes

The human nervous system handles vast amounts of information by translating sensory stimuli into neural impulses, which the brain processes, creating thoughts expressed through language or stored as memories. The brain also synthesizes information from emotions and memories, which significantly influence thoughts and behaviors. This intricate process creates a comprehensive mental picture.
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...

Formula Mass and Mole Concepts of Compounds

Formula Mass and Mole Concepts of Compounds

Formula Mass of Covalent Compounds

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Left Ventricular Global Longitudinal Strain Is Associated With Appropriate Therapies for Ventricular Arrhythmias Independent of Left Ventricular Ejection Fraction in Patients With Primary Prevention Defibrillators.

Journal of arrhythmia·2026

Same author

Which Patient Benefits from Guideline-directed Medical Therapy for Heart Failure and Rate Control versus Rhythm Control in Patients with Congestive Heart Failure and Atrial Fibrillation and What are Those Therapies?

Arrhythmia & electrophysiology review·2026

Same author

Patient health or corporate profits-Shouldn't the former come first?

The American journal of medicine·2026

Same author

Trial emulation of percutaneous left atrial appendage occlusion versus direct oral anticoagulants.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026

Same author

Corrigendum to '2025 SCAI/HRS Clinical Practice Guidelines on Transcatheter Left Atrial Appendage Occlusion': [Journal of the Society for Cardiovascular Angiography & Interventions. Volume 4, Issue 9 (2025) 103783].

Journal of the Society for Cardiovascular Angiography & Interventions·2026

Same author

Pulse field ablation versus thermal ablation: A systematic review and meta analysis of randomized controlled trials.

Trends in cardiovascular medicine·2026

Search research articles

Related Experiment Video

Updated: Feb 6, 2026

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

Cardiac automaticity: basic concepts and clinical observations.

Hector M Vetulli¹, Marcelo V Elizari², Gerald V Naccarelli³

¹Electrophysiology Department, Sanatorio Otamendi and Universidad de Buenos Aires, Buenos Aires, Argentina.

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing

|August 17, 2018

Summary

This summary is machine-generated.

Cardiac automaticity arises from complex membrane interactions. Clinical observations reveal that pacemaker sites are widely distributed within and outside the crista terminalis in patients with sinus tachycardia and dominant pacemakers.

Keywords:

Calcium clock Cardiac automaticity Sinus node

More Related Videos

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Published on: June 10, 2012

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Related Experiment Videos

Last Updated: Feb 6, 2026

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Published on: June 10, 2012

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Area of Science:

Cardiology
Electrophysiology
Cardiac Physiology

Background:

Cardiac automaticity is fundamental to heart rhythm.
Sinus automaticity, originating from the sinoatrial node, typically resides within the crista terminalis.
Understanding variations in pacemaker location is crucial for managing certain cardiac arrhythmias.

Purpose of the Study:

To review the fundamental mechanisms of cardiac automaticity.
To analyze clinical observations of anatomical and functional characteristics of sinus automaticity.
To investigate pacemaker site distribution in specific patient populations.

Main Methods:

Reviewed established discoveries on cardiac automaticity mechanisms.
Analyzed clinical data from patients with inappropriate sinus tachycardia (IST) and dominant ectopic pacemakers.
Utilized non-contact and high-density contact endocardial mapping techniques.

Main Results:

Inappropriate sinus tachycardia patients showed a wide distribution of atrial pacemaker sites, both within and outside the crista terminalis.
Patients with dominant pacemakers outside the crista terminalis had pacemakers located in the right atrial appendage, left atrial appendage, or mitral annulus.
Radiofrequency ablation shifted earliest atrial activation to the crista terminalis at a slower rate.

Conclusions:

Cardiac automaticity results from the interplay of membrane and sub-membrane mechanisms.
Pacemaker sites are not confined to the crista terminalis, exhibiting a broad distribution.
These findings have implications for understanding and managing arrhythmias related to ectopic pacemaker activity.