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Bethanechol: Is it still being prescribed for bladder dysfunction in women?
Shivani Gaitonde1, Rena D Malik1, Alana L Christie1
1Department of Urology, UT Southwestern Medical Center, Dallas, Texas.
International Journal of Clinical Practice
|August 17, 2018
Summary
Bethanechol is still prescribed for elderly women with bladder issues like atony and urinary retention. This study analyzed its use in ambulatory care settings over a decade.
Area of Science:
- Urology
- Pharmacology
- Public Health
Background:
- Limited medical treatment options exist for detrusor underactivity and urinary retention in women.
- Bethanechol, a cholinergic agonist, may improve detrusor contractility but has limited clinical efficacy.
Purpose of the Study:
- To examine the prescribing patterns of Bethanechol in an ambulatory care setting.
- To determine if Bethanechol is still prescribed for women with bladder dysfunction using a national database.
Main Methods:
- The National Ambulatory Medical Care Survey (NAMCS) database was queried for patient visits from 2003-2013.
- Included visits were for women aged 18+ with diagnoses of lower urinary tract symptoms, neurogenic bladder, or urinary retention.
- Descriptive statistics were used to analyze visits where Bethanechol was prescribed.
Main Results:
- Bethanechol was prescribed in 0.8% of 17,321,630 analyzed patient visits.
- The mean age of patients prescribed Bethanechol was 62.3 years, predominantly Caucasian.
- Primary diagnoses included atony of bladder (35%), urinary retention (20%), and neurogenic bladder (18%).
Conclusions:
- Bethanechol continues to be prescribed for elderly women.
- The primary indications are detrusor atony, urinary retention, and incomplete bladder emptying.
- Urologists predominantly prescribed Bethanechol as a continued medication.
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