Related Experiment Video
Updated: Feb 6, 2026

Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx
Published on: May 2, 2025
The Role of Advanced Glycation End Products in Diabetic Vascular Complications
Sang Youl Rhee1, Young Seol Kim2
1Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Abstract:
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.
More Related Videos
08:10An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy
Published on: January 25, 2019
05:08Plate-based Large-scale Cultivation of Caenorhabditis elegans: Sample Preparation for the Study of Metabolic Alterations in Diabetes
Published on: August 24, 2018
Related Concept Videos
Diabetes: Symptoms, Diagnosis, and Complications
Hemodialysis II: Procedure and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Seedless Vascular Plants
Pneumonia III: Complications and Assessment
Asthma-III: Symptoms and Complications
Classification of Asthma