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Acute Hemorrhagic Edema of Infancy With Associated Hemorrhagic Lacrimation

Hannah Sneller, Carolina Vega1, Lawrence Zemel

  • 1Department of Pediatrics, University of Connecticut School of Medicine.

Pediatric Emergency Care
|August 17, 2018
PubMed

Insights

Acute hemorrhagic edema of infancy, a rare vasculitis, presents with purpuric skin lesions in young children. This case highlights unusual hemorrhagic lacrimation and epistaxis as accompanying symptoms.

Area of Science:

  • Pediatric Dermatology
  • Pediatric Hematology
  • Pediatric Rheumatology

Background:

  • Acute hemorrhagic edema of infancy (AHEI) is a rare, self-limiting leukocytoclastic vasculitis.
  • Typically observed in children between 4 and 24 months of age.
  • Characterized by distinctive edematous purpuric skin lesions.

Observation:

  • A 5-month-old female infant presented with acute onset of purpuric lesions.
  • The infant also exhibited unusual symptoms of hemorrhagic lacrimation (bloody tears).
  • Associated epistaxis (nosebleeds) was noted concurrently with the skin lesions.

Findings:

  • The clinical presentation was consistent with acute hemorrhagic edema of infancy.
  • The presence of hemorrhagic lacrimation and epistaxis represents an atypical manifestation.
  • Leukocytoclastic vasculitis was suspected based on the clinical and pathological findings.

Implications:

  • This case expands the spectrum of clinical manifestations for AHEI.
  • Highlights the importance of considering AHEI in infants with purpuric lesions and unusual bleeding.
  • Further research may elucidate the pathophysiology behind these atypical hemorrhagic symptoms in AHEI.

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