Home oxygen therapy criteria, guidelines and protocols for hypoxia management in pediatric patients with acute

Terra Watkins1,2, Shelia Keller3,2

  • 1University of Mississippi Medical Center, Jackson, USA.

Insights

This review examines discharge criteria for home oxygen therapy (HOT) in pediatric acute bronchiolitis. It identifies current practices and gaps in guidelines for managing hypoxia at home.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Guidelines

Background:

  • Acute bronchiolitis is a common pediatric respiratory illness.
  • Hypoxia management is crucial, often involving home oxygen therapy (HOT).
  • Standardized discharge criteria for HOT are lacking.

Purpose of the Study:

  • To explore literature on discharge criteria, guidelines, and protocols for HOT in pediatric acute bronchiolitis.
  • To conceptually map existing evidence.
  • To identify gaps in current literature.

Main Methods:

  • Scoping review methodology.
  • Systematic literature search for relevant studies.
  • Thematic analysis and evidence mapping.

Main Results:

  • The review identified varied discharge criteria and protocols for HOT.
  • Significant heterogeneity exists in current clinical practices.
  • Gaps were noted in evidence-based guidelines for HOT discontinuation.

Conclusions:

  • There is a need for standardized, evidence-based discharge criteria for HOT in pediatric acute bronchiolitis.
  • Further research is required to develop and validate optimal protocols.
  • Improved guidelines can enhance safe and effective home management of hypoxia.
Abstract

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
266
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
314
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
237
The Scope of Physics01:17

The Scope of Physics

Physics is concerned with the interactions of energy, matter, space, and time, in order to discover the underlying mechanisms that underpin all phenomena. The word "physics" comes from the Greek word "phúsis", which means nature. Physics seeks to comprehend the natural world around us at its most fundamental level. It emphasizes the use of quantitative laws to do this, which could be valuable in other fields that want to push the performance boundaries of present...
53.2K
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
305
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
425