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[Changes of the auditory function in he children with chronic kidney failure]
V V Barilyak1, N A Mileshina2, Yu A Moskalets3
1Department of Audiology of the Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, Moscow, Russia, 125995.
Vestnik Otorinolaringologii
|August 17, 2018
Summary
Children with chronic kidney failure (CRF) face a higher risk of hearing loss due to disease complications and treatments. High-dose immunosuppressants and aminoglycosides are key factors contributing to this hearing impairment.
Area of Science:
- Nephrology
- Otolaryngology
- Pediatrics
Background:
- Chronic kidney failure (CRF) presents unique risks for pediatric patients.
- The cochlea's structure shares similarities with the nephron, suggesting potential auditory vulnerability.
- Disease manifestations and treatment side effects are primary contributors to hearing loss in children with CRF.
Purpose of the Study:
- To evaluate auditory function in children diagnosed with chronic kidney failure.
- To identify the prevalence and characteristics of hearing loss in pediatric CRF patients.
Main Methods:
- A cohort of 62 children with CRF was assessed.
- Transient evoked otoacoustic emission (TEOAE) testing was conducted on all participants.
- Comprehensive audiological examinations were performed for children lacking TEOAE responses.
Main Results:
- 17 out of 62 children showed no TEOAE response.
- 13 children exhibited hearing loss of varying degrees, and 5 presented with bilateral deafness.
- Prolonged CRF duration correlated with increased susceptibility to hearing impairment.
Conclusions:
- Hearing loss is a significant concern in pediatric chronic kidney failure.
- High-dose immunosuppressants and aminoglycosides are identified as major etiological factors.
- Genetic factors may also play a role in the development of hearing loss in this population.
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