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Related Experiment Videos

Atypical social cognitive processing in premotor Huntington's disease: a single case study.

T Burke1, D Healy2, P Casey3

  • 11Department of Psychology,Beaumont Hospital,Dublin 9,Ireland.

Irish Journal of Psychological Medicine
|August 18, 2018
PubMed
Summary

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Pre-motor Huntington's disease (HD) can cause significant behavioral and social deficits before motor symptoms appear. Early recognition of these cognitive changes is crucial for managing the impact on a patient's life.

Area of Science:

  • Neuroscience
  • Neurology
  • Clinical Case Study

Background:

  • Presents a case of a 52-year-old male with pre-motor Huntington's disease (HD).
  • Highlights significant negative symptomatology and behavioral changes impacting social and occupational life.
  • Notes the absence of overt motor symptoms at this stage.

Purpose of the Study:

  • To detail the clinical and neuropsychological presentation of pre-motor Huntington's disease.
  • To emphasize the impact of non-motor symptoms on patient's functional ability.
  • To illustrate early social cognitive deficits in HD.

Main Methods:

  • Detailed clinical examination.
  • Repeat neuropsychological testing focusing on executive function and social cognition.
Keywords:
Affect deficitHuntington’s diseaseempathysocial-cognition

Related Experiment Videos

  • Longitudinal assessment over two years (ages 50 and 52).

    • Main Results:

    • Identified behavioral, psychiatric, and social-affective deficits.
    • Demonstrated significant impact on social, occupational, and interpersonal functioning.
    • Documented changes in executive function and social cognition.

    Conclusions:

    • Social cognitive changes can precede motor symptoms in Huntington's disease by months or years.
    • Unrecognized deficits can severely impact an individual's lifestyle and functional capacity.
    • This case underscores the importance of recognizing non-motor symptoms for early HD diagnosis and management.