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Physical activity and sedentary behavior thresholds for identifying childhood hypertension and its phenotypes: The
Kalliopi Karatzi1, George Moschonis2, Sofia Botelli1
1Department of Nutrition and Dietetics, School of Health Science & Education, Harokopio University of Athens, Greece.
Insights
Increased physical activity and reduced sedentary behavior are linked to lower hypertension risk in children. Specific thresholds for daily steps, moderate-to-vigorous activity, and screen time identify children at higher risk for hypertension.
Area of Science:
- Pediatrics
- Cardiology
- Public Health
Background:
- Hypertension phenotypes are poorly understood despite potential differences in pathophysiology and clinical outcomes.
- Investigating lifestyle factors like physical activity and sedentary behavior is crucial for understanding childhood hypertension.
Purpose of the Study:
- To examine the associations between physical activity, sedentary behavior, and hypertension phenotypes in Greek schoolchildren.
- To identify risk thresholds for hypertension based on these lifestyle factors.
Main Methods:
- A cross-sectional study of 2473 schoolchildren aged 9-13 years.
- Data collected included physical activity (steps/day, moderate-to-vigorous physical activity - MVPA), sedentary behavior (screen time), blood pressure, and anthropometry.
Main Results:
- Hypertensive children had lower physical activity levels. Boys with isolated systolic hypertension (ISH) had higher screen time.
- Increased physical activity was associated with 33%-54% lower risk of all hypertension phenotypes. Increased MVPA showed even greater risk reduction (41%-65%).
- Higher sedentary time in boys was linked to an 11%-13% increased risk of ISH and systolic and diastolic hypertension (SDH). Identified thresholds: 12,378 steps/day, 47.3 min/day MVPA, 2.9 h/day sedentary behavior.
Conclusions:
- Physical activity is inversely associated with hypertension phenotypes in children.
- Sedentary behavior is positively associated with ISH and SDH in boys.
- Identified cutoff values require confirmation for use in childhood hypertension prevention programs.
Abstract:
Hypertension phenotypes may represent differential pathophysiologic mechanisms and clinical impact, yet they have been poorly investigated. The study aimed to examine the associations of physical activity and sedentary behavior with hypertension phenotypes in a large group of Greek children and to identify thresholds regarding risk of hypertension. This was a cross-sectional study with a regionally representative sample of 2473 schoolchildren aged 9-13 years, with full data on physical activity and sedentary behavior indices, as well as arterial blood pressure measurements, physical examination, and anthropometry. Hypertensive children of both sexes had lower levels of physical activity (steps/d). Hypertensive girls had lower moderate-to-vigorous physical activity (MVPA), whereas hypertensive boys with isolated systolic hypertension (ISH) had more screen time than their normotensive counterparts. Increased levels of physical activity was associated with 33%-54% lower risk of all hypertension phenotypes in both sexes, whereas increased MVPA was associated with 41%-65% lower risk of all phenotypes in girls and with ISH and systolic and diastolic hypertension (SDH) in boys. In boys, higher sedentary time was associated with 11%-13% higher risk for SDH and ISH. Cutoff points of 12,378 steps/d, 47.3 min/d of MVPA, and 2.9 h/d of sedentary behavior were determined for identifying children at increased risk of hypertension. Physical activity is inversely associated with all hypertension phenotypes, whereas sedentary behavior is positively associated with ISH and SDH in boys. More studies should confirm the hypertension-specific cutoff values identified to be used in future prevention programs for childhood hypertension.
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