Understanding the Relationship between Atherogenic Index of Plasma and Cardiovascular Disease Risk Factors among Staff of an University in Malaysia
Myat Su Bo1, Whye Lian Cheah2, Soe Lwin3
1Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia.
Insights
The Atherogenic Index of Plasma (AIP) is linked to cardiovascular disease risk factors. Lifestyle changes are recommended to manage these risks and improve health outcomes.
Area of Science:
- Biochemistry
- Cardiovascular Health
- Public Health
Background:
- The Atherogenic Index of Plasma (AIP) is a significant predictor of cardiovascular disease (CVD) risk.
- Understanding AIP's relationship with other CVD risk factors is crucial for preventative strategies.
Purpose of the Study:
- To determine the Atherogenic Index of Plasma (AIP) in a university staff population.
- To investigate the association between AIP and various cardiovascular disease risk factors.
Main Methods:
- A cross-sectional study involving 349 university staff in Sarawak.
- Data collection included questionnaires, blood sampling, anthropometric measurements, and blood pressure readings.
- Statistical analysis was performed using IBM SPSS version 20.
Main Results:
- A significant portion of participants were overweight/obese with high body fat and abnormal visceral fat.
- Elevated lipid profiles (total cholesterol, LDL, triglycerides) were observed in a notable percentage of respondents.
- AIP showed significant correlations with body mass index, visceral fat, lipid profiles, glucose levels, and blood pressure.
Conclusions:
- Atherogenic Index of Plasma (AIP) is demonstrably associated with multiple cardiovascular disease risk factors.
- Lifestyle modifications are strongly advised for individuals with elevated AIP and associated risk factors.
Background:
Atherogenic index of plasma (AIP) was found to be one of the strongest markers in predicting the cardiovascular disease (CVD) risk. This study was to determine the AIP and its relationship with other CVD risk factors.
Materials And Methods:
This cross-sectional study was done among 349 staff of a public university in Sarawak. Data were collected using questionnaire, blood sampling, and anthropometric and blood pressure measurement. Data were analyzed using IBM SPSS version 20.
Results:
A total of 349 respondents participated with majority females (66.8%), aged 38.5 ± 7.82 years. Nearly 80% of the respondents were overweight and obese, 87.1% with high and very high body fat, and 46.9% with abnormal visceral fat. For AIP category, 8.9% were found to be in intermediate and 16.4% were at high risk. Elevated lipid profile showed that total cholesterol (TC) is 15.5%, low density lipoprotein (LDL) is 16.1%, and triglyceride (TG) is 10.6%. AIP was significantly correlated with body mass index (r=0.25), visceral fat (r=0.37), TC (r=0.22), LDL (0.24), HDL (r=-0.72), TG (r=0.84), glucose (r=0.32), systolic blood pressure (r=0.22), and diastolic blood pressure (r=0.28).
Conclusion:
It indicated that AIP is associated with other CVD risk factors. Modification of lifestyle is strongly recommended.
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